夫西地酸對新生兒和小嬰兒血清膽紅素水平的影響
發(fā)布時間:2018-05-07 15:17
本文選題:夫西地酸 + 膽紅素; 參考:《中國感染與化療雜志》2017年03期
【摘要】:目的探討新生兒和小嬰兒應(yīng)用夫西地酸后血清膽紅素的變化。方法對2012-2014年青島市婦女兒童醫(yī)院應(yīng)用夫西地酸的半歲以下患兒用藥前后的血清膽紅素等指標(biāo)進(jìn)行回顧性分析,比較用藥前后的血清膽紅素變化情況。結(jié)果所有138例應(yīng)用夫西地酸治療的患兒,治療后均未出現(xiàn)新發(fā)黃疸或原有黃疸加重的情況;其中64例用藥前后檢測了血生化指標(biāo),治療前后白蛋白、丙氨酸轉(zhuǎn)氨酶、天冬氨酸轉(zhuǎn)氨酶等均無顯著差異,治療后的間接膽紅素與總膽紅素比值(Ibil/Tbil)比用藥前下降了約8%。結(jié)論該系列應(yīng)用夫西地酸的患兒中未見該藥對血清膽紅素水平的明顯影響。
[Abstract]:Objective to investigate the changes of serum bilirubin in newborns and small infants. Methods the indexes of serum bilirubin before and after treatment were analyzed retrospectively and the changes of serum bilirubin in Qingdao Women and Children Hospital from 2012 to 2014 were compared. Results none of 138 children treated with fossillic acid had new jaundice or aggravation of the original jaundice after treatment, and 64 of them detected serum biochemical indexes, albumin and alanine aminotransferase before and after treatment. The ratio of indirect bilirubin to total bilirubin decreased by about 8% compared with that before treatment. Conclusion the serum bilirubin level was not significantly affected by this series of children with fusidic acid.
【作者單位】: 青島市婦女兒童醫(yī)院藥劑科;
【分類號】:R725.1
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本文編號:1857430
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