本文選題：CV + EV�。� 參考：《中國(guó)病原生物學(xué)雜志》2017年11期

【摘要】：目的對(duì)柯薩奇病毒A6型(CA6)所致手足口病患兒流行特征及臨床表現(xiàn)進(jìn)行分析,為該病的預(yù)防控制提供科學(xué)依據(jù)。方法收集2016年1~12月海南省婦幼保健院兒科手足口病患兒的臨床資料進(jìn)行描述性流行病學(xué)分析;采集患兒肛拭子標(biāo)本,使用熒光定量PCR試劑盒進(jìn)行病毒核酸檢測(cè),分析其結(jié)果。結(jié)果 1 368例手足口病患者中檢出EV71感染287例(占20.98%),CA16感染228例(占16.67%),CA6感染179(占13.08%%)。CA6感染組男女比例為1.89∶1,CA16感染組男女比例為1.23∶1差異有統(tǒng)計(jì)學(xué)意義(χ~2=4.620,P0.05);CA6感染組平均年齡為(2.91±2.12)歲,EV71及CA16感染者平均年齡分別為(3.49±2.19)歲和(3.38±2.11)歲,差異均有統(tǒng)計(jì)學(xué)意義(P0.05);CA6組皮疹易出現(xiàn)在軀干,與其他兩組相比差異有統(tǒng)計(jì)學(xué)意義(χ~2=9.568,P0.05);CV6組與EV71組相比皮疹較少出現(xiàn)在足部,兩組間差異有統(tǒng)計(jì)學(xué)意義(χ~2=5.614,P0.05);CA6組發(fā)熱率75.61%,與EV71組(51.22%)和CA16(47.37%)比較差異均有統(tǒng)計(jì)學(xué)意義(χ~2=23.339,P0.05);EV71組和CA16組病例主要集中發(fā)生在4~8月份,CA6組主要發(fā)生在7~10月,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論 CA6為兒童手足口病新的流行病原之一,其發(fā)病的平均年齡較小,多數(shù)患兒有發(fā)熱癥狀,皮疹呈多樣性,且多出現(xiàn)在軀干,流行高峰期為7~11月份。
[Abstract]:Objective to analyze the epidemic characteristics and clinical manifestations of children with hand foot and mouth disease (HFMD) caused by coxsackievirus A6 (CA6), and to provide scientific basis for the prevention and control of the disease. Methods the clinical data of children with hand foot and mouth disease in Hainan maternal and child health care hospital of 2016 were collected and analyzed by descriptive flow disease analysis, and the specimens of children's anal swabs were collected and used. The results showed that 287 cases (20.98%) were detected in 1368 cases of hand foot and mouth disease, 228 cases of CA16 infection (16.67%), 179 of CA6 infection (13.08%%).CA6 infection group of 1.89: 1 in 1368 cases of hand foot and mouth disease, and the proportion of men and women in CA16 infection group was 1.23: 1 (P0. (P0.), P0. (P0.). 05): the average age of CA6 infection group was (2.91 + 2.12) years, the average age of EV71 and CA16 infected people was (3.49 + 2.19) years and (3.38 + 2.11) years, the difference was statistically significant (P0.05). The skin rash in CA6 group was easy to appear in the trunk, compared with the other two groups (x ~2=9.568, P0.05); CV6 group was less in foot rash compared with EV71 group. The difference between the two groups was statistically significant (x ~2=5.614, P0.05), the fever rate in group CA6 was 75.61%, compared with group EV71 (51.22%) and CA16 (47.37%), there were statistical significance (x ~2=23.339, P0.05), EV71 and CA16 group cases mainly occurred in 4~8 month, CA6 group occurred mainly in 7~10 month, the difference was statistically significant. Conclusion the conclusion is children. One of the new epidemic pathogens of hand foot and mouth disease, the average age of the disease is smaller, most of the children have fever symptoms, skin rash is diversity, and more in the trunk, the peak of epidemic is 7~11 month.

【作者單位】： 海南省婦幼保健院;
【分類(lèi)號(hào)】：R181.3;R725.1

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1 楊傲然;云南省手足口病流行特征及家庭內(nèi)感染狀況研究[D];昆明醫(yī)科大學(xué);2017年

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本文編號(hào)：1838953