本文選題：早產(chǎn)兒 + 矯正胎齡小于周��； 參考：《廣東醫(yī)學(xué)》2017年02期

【摘要】：目的確定矯正胎齡小于37周早產(chǎn)兒全憑吸入麻醉時(shí)拔除喉罩無(wú)體動(dòng)反應(yīng)的七氟烷最低肺泡有效濃度(MAC)。方法擇期全憑吸入全麻下行眼科手術(shù)的矯正胎齡小于37周的早產(chǎn)兒29例,ASA分級(jí)Ⅱ級(jí)。吸入6%七氟烷進(jìn)行全麻誘導(dǎo),手術(shù)過(guò)程中全憑吸入七氟烷維持麻醉。手術(shù)結(jié)束后,將呼氣末七氟烷濃度調(diào)整至預(yù)定值,維持15 min不變,然后拔除喉罩。根據(jù)Dixon上下法進(jìn)行試驗(yàn),初始呼氣末七氟烷濃度為1.4%,拔除喉罩時(shí)發(fā)生體動(dòng)反應(yīng),下一例升高一個(gè)濃度梯度,拔除喉罩時(shí)未發(fā)生體動(dòng)反應(yīng),下一例降低一個(gè)濃度梯度,相鄰濃度梯度為0.2%。將無(wú)體動(dòng)反應(yīng)時(shí)呼氣末七氟烷濃度到體動(dòng)反應(yīng)時(shí)呼氣末七氟烷濃度的中點(diǎn)設(shè)為平衡點(diǎn),計(jì)算所有平衡點(diǎn)七氟烷濃度的平均值即為MAC。結(jié)果矯正胎齡小于37周早產(chǎn)兒拔除喉罩無(wú)體動(dòng)反應(yīng)的七氟烷MAC為(1.17±0.19)%。結(jié)論矯正胎齡小于37周早產(chǎn)兒拔除喉罩無(wú)體動(dòng)反應(yīng)的七氟烷MAC為(1.17±0.19)%,低于足月兒童的參考值,這可能是歸因于早產(chǎn)兒中樞神經(jīng)系統(tǒng)發(fā)育尚不完善。
[Abstract]:Objective to determine the minimum alveolar effective concentration of sevoflurane in preterm infants with corrected gestational age less than 37 weeks after total inhalation anesthesia. Methods 29 cases of preterm infants whose gestational age was less than 37 weeks were treated with selective general anesthesia with ASA grade 鈪，

本文編號(hào)：1801119