寒熱并用法治療“寒熱錯(cuò)雜型”兒童支氣管哮喘急性發(fā)作期的臨床研究
本文選題:解表清里、化痰平喘方 + 兒童支氣管哮喘; 參考:《廣州中醫(yī)藥大學(xué)》2012年碩士論文
【摘要】:目的: 通過(guò)對(duì)研究對(duì)象治療前后及組間相關(guān)療效指標(biāo)比較,綜合評(píng)價(jià)解表清里、化痰平喘方治療兒童哮喘急性發(fā)作期的療效。初步探討應(yīng)用解表清里、化痰平喘方治療急性發(fā)作期兒童支氣管哮喘的療效明確且顯著,從而為其在臨床上的推廣運(yùn)用奠定基礎(chǔ)。 方法: 把符合研究標(biāo)準(zhǔn)的60例患兒,隨機(jī)分組,按1:1分為治療組及對(duì)照組。治療組給予西藥常規(guī)治療+解表清里、化痰平喘方,每日一劑;對(duì)照組給予西藥常規(guī)治療。兩組療程均為5天。通過(guò)對(duì)治療前和治療后分別進(jìn)行癥狀及體征積分觀察,和肺功能的檢測(cè),運(yùn)用SPASS17.0統(tǒng)計(jì)軟件進(jìn)行分析,觀察兩組的療效差異,評(píng)價(jià)解表清里、化痰平喘方治療兒童哮喘急性發(fā)作期的臨床療效。 成果: 1.治療5天后,治療組與對(duì)照組均能有效改善患兒的總臨床癥狀,治療前后比較有顯著性差異(P0.05),其中治療組在改善總臨床癥狀上,療效優(yōu)于對(duì)照組,具有統(tǒng)計(jì)學(xué)意義(P0.05)。 2.治療組與對(duì)照組在中醫(yī)總癥狀治療前后積分變化的比較,有顯著性差異(P0.05),其中治療組總癥狀積分變化大于對(duì)照組,治療組在改善癥狀方面優(yōu)于對(duì)照組,具有統(tǒng)計(jì)學(xué)意義(P0.05)。 3.治療組與對(duì)照組中醫(yī)主癥的臨床控制的比較,及兩組起效時(shí)間的比較,均有顯著性差異(P0.05),其中治療組在中醫(yī)主癥的臨床控制、起效時(shí)間上,療效優(yōu)于對(duì)照組,具有統(tǒng)計(jì)學(xué)意義(P0.05)。 4.治療5天后,治療組與對(duì)照組均能有效改善肺功能(PEF、FEV1),治療前后比較有顯著性差異(P0.05),其中治療組在改善肺功能方面優(yōu)于對(duì)照組,具有統(tǒng)計(jì)學(xué)意義(P0.05)。 結(jié)論: 研究結(jié)果顯示,應(yīng)用解表清里、化痰平喘方治療急性發(fā)作期兒童支氣管哮喘的療效明確且顯著,可更快地控制哮喘,減輕或消除患兒的相關(guān)臨床癥狀。
[Abstract]:Objective: To evaluate the efficacy of Huatan Pingchuan prescription in treating children with asthma in acute attack stage by comparing the related therapeutic indexes before and after treatment and between groups. To explore the curative effect of Huatan Pingchuan prescription in treating acute asthma in children with acute attack, and to lay a foundation for its clinical application. Methods: According to the study criteria, 60 children were randomly divided into treatment group and control group according to 1:1. The treatment group was treated with routine treatment of western medicine, Huatan Pingchuan prescription, once a day, while the control group was given routine treatment of western medicine. The course of treatment was 5 days in both groups. The symptoms and signs were observed before and after treatment, and the pulmonary function was detected. The difference of curative effect between the two groups was observed by using SPASS17.0 software, and the difference between the two groups was evaluated. Clinical effect of Huatan Pingchuan decoction on Acute attack of Children Asthma. Outcome: 1. After 5 days of treatment, both the treatment group and the control group could effectively improve the total clinical symptoms of the children. There was a significant difference between the two groups before and after treatment (P 0.05). The therapeutic effect of the treatment group in improving the total clinical symptoms was better than that in the control group (P 0.05). 2. There was significant difference between the treatment group and the control group in the change of the integral before and after the treatment of total symptoms of TCM, among which the change of the total symptom integral of the treatment group was greater than that of the control group, and the treatment group was superior to the control group in improving the symptoms, which had statistical significance. 3. There were significant differences in the clinical control and the onset time between the treatment group and the control group, among which the treatment group was better than the control group in the clinical control and onset time of the main symptoms of TCM, and had statistical significance (P 0.05). 4. After 5 days of treatment, both the treatment group and the control group were able to improve the pulmonary function effectively. There was a significant difference before and after treatment (P 0.05), and the treatment group was better than the control group in improving the lung function, which had statistical significance (P 0.05). Conclusion: The results showed that the curative effect of Huatan Pingchuan decoction on acute asthma in children was clear and remarkable. It could control asthma more quickly and relieve or eliminate the related clinical symptoms of children.
【學(xué)位授予單位】:廣州中醫(yī)藥大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2012
【分類(lèi)號(hào)】:R272
【參考文獻(xiàn)】
相關(guān)期刊論文 前10條
1 黎同明,孫志佳,劉小虹,梁直英;定喘湯治療哮喘發(fā)作期熱哮型的臨床研究[J];安徽中醫(yī)學(xué)院學(xué)報(bào);2005年01期
2 鄭仰明,李昌崇;支氣管哮喘和衛(wèi)生假說(shuō)[J];國(guó)外醫(yī)學(xué)(兒科學(xué)分冊(cè));2005年02期
3 王元;瞿彩云;彭雪晶;;甘草及其衍生物藥理作用的研究新進(jìn)展[J];甘肅醫(yī)藥;2011年07期
4 徐艷琴;;射干麻黃湯治療支氣管哮喘臨床及實(shí)驗(yàn)研究概況[J];國(guó)醫(yī)論壇;2008年04期
5 劉素文;劉昌玉;羅菲;張晶櫻;;小青龍湯治療小兒寒哮的臨床觀察[J];湖北中醫(yī)學(xué)院學(xué)報(bào);2003年04期
6 馮艷;;穴位貼敷防治小兒哮喘的臨床觀察[J];全科護(hù)理;2010年11期
7 張敏,馮家銀,黃少玲;推拿療法治療小兒哮喘的研究[J];江西中醫(yī)藥;2002年04期
8 高浩學(xué);丁安偉;唐于平;張旭;;葦莖的化學(xué)成分、藥理作用與臨床應(yīng)用研究進(jìn)展[J];現(xiàn)代中藥研究與實(shí)踐;2009年03期
9 劉慶芳;;大青龍湯藥效研究與應(yīng)用[J];河南大學(xué)學(xué)報(bào)(醫(yī)學(xué)版);2006年04期
10 徐艷;何成詩(shī);;支氣管哮喘的免疫治療進(jìn)展[J];實(shí)用臨床醫(yī)學(xué);2011年03期
,本文編號(hào):1789363
本文鏈接:http://sikaile.net/yixuelunwen/eklw/1789363.html