本文關(guān)鍵詞：肺炎患兒血清維生素A、D水平研究　出處：《重慶醫(yī)科大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

  更多相關(guān)文章： 維生素A 維生素D 兒童 肺炎

【摘要】：目的分別探討肺炎患兒體內(nèi)維生素A(Vitamin A,VA)、維生素D(Vitamin D,VD)狀況及其與肺炎和病后反復(fù)呼吸道感染的關(guān)系。方法選取88例因肺炎于我院呼吸中心住院治療患兒為研究對象,入院時檢測其血清維生素A及維生素D水平,同時收集患兒臨床資料及電話隨訪其病后一年內(nèi)呼吸道感染情況。(1)比較性別間及不同年齡組間血清維生素A、D水平。(2)以流行病學(xué)調(diào)查全國兒童血清VA平均水平為參照,分析肺炎患兒體內(nèi)VA水平。(3)以目前研究報道的我國西部地區(qū)兒童血清VD平均水平為參照,分析肺炎患兒體內(nèi)VD水平。(4)88例肺炎患兒按病情輕重分為重癥肺炎組和普通肺炎組,比較兩組間血清維生素A、D水平。(5)按體內(nèi)VA水平高低分為VA缺乏組、可疑亞臨床VA缺乏組以及VA正常組,比較三組間病后一年內(nèi)反復(fù)呼吸道感染(Recurrent respiratory tract infection,RRI)發(fā)生率。(6)按病后一年內(nèi)是否發(fā)生反復(fù)呼吸道感染分為RRI組及非RRI組,比較兩組間血清VD水平。結(jié)果不同性別及年齡間血清維生素A、D水平均無統(tǒng)計學(xué)差異(P0.05);肺炎患兒體內(nèi)維生素A、D水平均低于人群中兒童平均水平;重癥肺炎組血清維生素A、D水平均低于普通肺炎組(P0.05);VA缺乏組病后一年內(nèi)RRI發(fā)生率明顯高于VA正常組;病后一年內(nèi)發(fā)生RRI組血清VD水平明顯低于未發(fā)生RRI組(P0.05)。結(jié)論本研究中血清維生素A、D水平與性別、年齡無關(guān);肺炎患兒體內(nèi)維生素A、D水平普遍低下;體內(nèi)維生素A、D水平高低與肺炎病情輕重及病后再感染風(fēng)險相關(guān),維生素A、D水平越低,越易發(fā)展為重癥,病后再感染風(fēng)險越高。
[Abstract]:Objective to explore the relationship between Vitamin A (VA) and vitamin A (Vitamin D, VD) in children with pneumonia and their relationship with recurrent respiratory tract infection after pneumonia. Methods a total of 88 children hospitalized for pneumonia in our respiratory center were selected as the subjects. Their serum vitamin A and vitamin D levels were detected at the time of admission, and the clinical data and telephone follow-up of respiratory tract infections during the first year after the disease were collected. (1) the serum levels of vitamin A and D were compared between the sexes and different age groups. (2) the VA level in children with pneumonia was analyzed with the reference of the average level of serum VA in the whole country. (3) according to the average level of VD in children's serum in Western China, the level of VD in children with pneumonia was analyzed. (4) 88 cases of pneumonia were divided into severe pneumonia group and common pneumonia group according to the severity of the disease. The serum levels of vitamin A and D were compared between the two groups. (5) according to the level of VA in the body, they were divided into VA deficient group, suspicious subclinical VA deficiency group and VA normal group. The incidence of recurrent respiratory tract infection (Recurrent respiratory tract infection) was compared between the three groups in one year. (6) according to the incidence of recurrent respiratory infection within one year after the disease, it was divided into RRI group and non RRI group, and the serum level of VD was compared between the two groups. Results there were no statistical differences in the level of serum vitamin A, D, age and gender (P0.05); pneumonia in children with vitamin A and D were lower than the average level of the crowd of children with severe pneumonia group; serum vitamin A and D were lower than the ordinary pneumonia group (P0.05); group VA deficiency disease within one year after the occurrence of RRI the rate of VA was significantly higher than that of the normal group; disease within one year after the occurrence of the serum level of VD in group RRI was significantly lower than non RRI group (P0.05). Conclusion in this study, the serum vitamin A level of D has nothing to do with sex and age; pneumonia in children with vitamin A, vitamin D level is generally low; the level of A, D and pneumonia severity and disease after infection risk of vitamin A, the lower the level of D, the more likely to develop into severe disease after infection. The higher the risk.
【學(xué)位授予單位】：重慶醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2016
【分類號】：R725.6

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