本文選題：尿液 + 鄰苯二甲酸酯類(lèi)化合物��； 參考：《中國(guó)環(huán)境科學(xué)》2017年08期

【摘要】：基于2013~2014年在上海地區(qū)開(kāi)展的中國(guó)室內(nèi)環(huán)境與兒童健康研究,分析了434位學(xué)齡兒童的晨尿PAEs代謝物濃度總體分布情況;并根據(jù)隨訪問(wèn)卷獲取的居室建筑特性信息,分析了PAEs代謝物與居室地板和墻面裝飾材料的關(guān)系.我們利用HPLC-MS/MS法對(duì)兒童晨尿中10種PAEs代謝物進(jìn)行定量檢測(cè),并采用非參數(shù)檢驗(yàn)法比較了居室使用不同類(lèi)型的地板和墻面裝飾材料的兒童晨尿中PAEs代謝物的濃度差異.除MBz P(檢出率:51.2%)和MCHP(9.9%)外,其他8種PAEs代謝物檢出率均在90%以上.代謝物濃度[中位數(shù)(標(biāo)準(zhǔn)差)]從高到低依次為:Mn BP,58.1(205.9)μg/L;Mi BP,46.2(119.2)μg/L;MECPP,39.0(111.1)μg/L;MEHHP,24.7(92.6)μg/L;MEOHP,14.5(45.1)μg/L;MMP,11.4(21.4)μg/L;MEP,10.1(51.5)μg/L;MEHP,4.5(19.0)μg/L;MBz P,0.2(4.3)μg/L;MCHP,LOD(0.2)μg/L.結(jié)果表明,男孩的代謝物濃度普遍高于女孩;10歲兒童的代謝物濃度普遍低于10歲的兒童;夏季代謝物濃度普遍高于其他季節(jié).中國(guó)兒童的DMP和DEHP代謝物濃度明顯高于其他國(guó)家或地區(qū).相對(duì)于水泥地板,客廳使用實(shí)木地板和復(fù)合木地板的兒童Mi BP濃度明顯更高;相對(duì)于實(shí)木地板,臥室使用復(fù)合木地板的兒童MEP和Mn BP濃度明顯更高;相對(duì)于石灰墻面,使用乳膠漆墻面和油漆墻面的兒童Mi BP濃度明顯更高.結(jié)果顯示上海地區(qū)學(xué)齡兒童尿液中PAEs代謝物個(gè)體水平存在較大差異;總體水平上存在性別、年齡和檢測(cè)季節(jié)的差異.居室使用復(fù)合木地板,乳膠漆和油漆等新型建材可能會(huì)明顯增加兒童的PAEs暴露量.
[Abstract]:Based on the Chinese indoor environment and children's health study conducted in Shanghai from 2013 to 2014, the distribution of PAEs metabolites in the morning urine of 434 school-age children was analyzed, and the characteristics of indoor buildings were obtained according to the follow-up questionnaire.The relationship between PAEs metabolites and indoor floor and wall decoration materials was analyzed.Ten metabolites of PAEs in children's morning urine were quantitatively detected by HPLC-MS/MS method, and the concentration differences of PAEs metabolites in children's morning urine with different types of floor and wall decoration materials were compared by nonparametric test.With the exception of MBz P (detectable rate: 51.2%) and MCHP (9.9%), the detectable rates of the other eight metabolites of PAEs were all above 90%.浠ｈ阿鐗╂祿搴涓綅鏁，

本文編號(hào)：1731285