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Introduction to Computational Molecular Biology

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A DNA helix rendered in ASCII art.

A DNA helix rendered in ASCII art. (Image courtesy of Ramona Saldamando. Used with permission.)

Instructor(s)

MIT Course Number

18.417

As Taught In

Fall 2004

Level

Graduate

Ocean Wave Interaction with Ships and Offshore Energy Systems (13.022)

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Some Description

Instructor(s)

Prof.

As Taught In

Spring 2002

Course Number

2.24

Level

Undergraduate/Graduate

Features

Lecture Notes, Student Work

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    Course Features

  • Selected lecture notes
  • Projects and examples
  • Course Description

    This course introduces the basic computational methods used to understand the cell on a molecular level. It covers subjects such as the sequence alignment algorithms: dynamic programming, hashing, suffix trees, and Gibbs sampling. Furthermore, it focuses on computational approaches to: genetic and physical mapping; genome sequencing, assembly, and annotation; RNA expression and secondary structure; protein structure and folding; and molecular interactions and dynamics.

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