2014-2015年四川省中醫(yī)院血培養(yǎng)病原菌分布及耐藥性分析
[Abstract]:Objective To analyze the distribution and drug resistance of blood culture positive pathogens in Sichuan Hospital of Traditional Chinese Medicine, and to provide evidence for clinical diagnosis and treatment. Methods A total of 6 271 blood samples were cultured by AC T/Alert 3D 60/120 automatic blood culture instrument from 2014 to 2015. The positive patients were identified by VITEK-2 Compact bacteria analysis and drug use. Results In 2014 and 2015, 2 808 blood samples and 3 463 blood samples were collected. The detection rates of pathogenic bacteria were 10.90% and 9.88% respectively. Gram-negative bacteria accounted for 61.43% and 56.30% respectively. The first three were Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumannii. Ampicillin resistance rate continued to be high (> 86.0%); Amoxicillin/clavulanate and quinolones resistance rate of Klebsiella pneumoniae increased from 37.50%, 18.75% to 81.25%, 50.00%; Acinetobacter baumannii resistance to ceftriaxone and aztreonam reached 100.00%. Coagulase-negative staphylococci, Staphylococcus aureus were found in Gram-positive bacteria. Staphylococcus epidermidis was resistant to penicillin and oxacillin. Among Staphylococcus aureus, the detection rate of MARSA increased from 22.22% to 34.78%. Staphylococcus epidermidis and Staphylococcus aureus were resistant to furantoin, tigacycline, vancomycin and linezolid. Conclusion The pathogen of bloodstream infection was found. Gram-negative bacteria are the main bacteria; pathogenic bacteria are resistant to commonly used antibiotics to varying degrees. Clinical surveillance of bacterial resistance should be strengthened. Clinicians should select antibiotics reasonably according to different bacteria and strictly abide by the guidelines for antibiotics use.
【作者單位】: 成都中醫(yī)藥大學(xué)醫(yī)學(xué)技術(shù)學(xué)院;四川省中醫(yī)院檢驗科;
【分類號】:R446.5
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