本文選題：醫(yī)用光學(xué)　切入點(diǎn)：血液分析儀　出處：《中國(guó)激光》2015年07期

【摘要】：傳統(tǒng)的五分類(lèi)血液分析儀一般與化學(xué)方法配合使用以提高白細(xì)胞的分類(lèi)精度,增加了儀器結(jié)構(gòu)的復(fù)雜程度和儀器的使用、維修成本。設(shè)計(jì)了一種特殊結(jié)構(gòu)的光學(xué)系統(tǒng),該系統(tǒng)引入了對(duì)后向散射光的檢測(cè),并采用直流(DC)信號(hào)、激光前向散射信號(hào)和后向散射信號(hào)相結(jié)合的方式實(shí)現(xiàn)了白細(xì)胞五分類(lèi)。實(shí)驗(yàn)結(jié)果表明裝有該系統(tǒng)的樣機(jī)對(duì)LYM、MON、NEU、EOS、BAS的分類(lèi)相對(duì)偏差均小于5%,其性能與血液分析儀Mythic 22接近。優(yōu)化后的光學(xué)系統(tǒng)可完成對(duì)白細(xì)胞的原位檢測(cè)和分類(lèi),且具有結(jié)構(gòu)簡(jiǎn)單、性能穩(wěn)定的特點(diǎn)。
[Abstract]:The traditional five-class blood analyzer is generally used in conjunction with chemical methods to improve the classification accuracy of white blood cells, increase the complexity of the structure of the instrument, the use of the instrument, maintenance costs, and design an optical system with a special structure. In this system, the backscattered light is detected and DC signal is used. By combining the laser forward scattering signal with the backward scattering signal, the five classification of white blood cells is realized. The experimental results show that the classification relative deviation of the prototype equipped with the system is less than 5%, and the performance of the system is connected with the blood analyzer Mythic 22. The optimized optical system can be used for in situ detection and classification of white blood cells. It has the characteristics of simple structure and stable performance.
【作者單位】： 南昌大學(xué)信息工程學(xué)院;南昌百特生物高新技術(shù)股份有限公司;
【基金】：國(guó)家自然科學(xué)基金(61261011)
【分類(lèi)號(hào)】：TH776
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本文編號(hào)：1683331