本文選題：質(zhì)子治療裝置　切入點：旋轉(zhuǎn)機架　出處：《中國科學(xué)院研究生院（上海應(yīng)用物理研究所）》2015年博士論文

【摘要】：質(zhì)子治療裝置是國際上新型治愈腫瘤的大型醫(yī)療設(shè)備，其中的旋轉(zhuǎn)機架（Gantry）具有結(jié)構(gòu)大、精度高的特點。上海質(zhì)子治療示范裝置是國內(nèi)首次對質(zhì)子治療技術(shù)的全面自主研發(fā)，其中新型的旋轉(zhuǎn)機架是具有180度回轉(zhuǎn)角度，旋轉(zhuǎn)半徑5.4m，重達162t的大型精密機械結(jié)構(gòu)。作為首臺國內(nèi)自主研發(fā)的旋轉(zhuǎn)機架，其瞄準目前國際上正在積極研發(fā)的新型半回轉(zhuǎn)的結(jié)構(gòu)，設(shè)計主體結(jié)構(gòu)與指標參數(shù)與國際接軌，具有空間大、重量輕、性價比高等特點。但由于參考資料匱乏、等中心精度要求極高、配套建筑設(shè)計復(fù)雜，同時又必須具備高性價比以適應(yīng)市場競爭，所以其設(shè)計難度極高。 本文先介紹了質(zhì)子治療技術(shù)的概況，然后較系統(tǒng)的介紹了目前國際上旋轉(zhuǎn)機架的發(fā)展以及試研時期的一些計算與分析。 本文的目的：為保證旋轉(zhuǎn)機架的結(jié)構(gòu)具有高性價比，必須在保證精度的情況下進行結(jié)構(gòu)優(yōu)化以大幅減輕整體重量，從而達到質(zhì)優(yōu)價廉。 采用的方法：采用物理優(yōu)化、經(jīng)驗設(shè)計優(yōu)化、拓撲優(yōu)化與尺寸優(yōu)化的多種方法綜合運用。 運用的主要結(jié)構(gòu)優(yōu)化設(shè)計的理論基礎(chǔ)：拓撲優(yōu)化ESO有限元法，尺寸優(yōu)化中的遺傳算法與序列二次規(guī)劃算法以及試驗設(shè)計方法與響應(yīng)面技術(shù)。 運用的軟件與計算過程：綜合采用Solidworks、ANSYS、Optimus軟件分別進行主要零件結(jié)構(gòu)的拓撲與尺寸優(yōu)化，文章重點闡述其主要優(yōu)化過程并對結(jié)構(gòu)進行驗算。 優(yōu)化的結(jié)果：通過對多個主要部件的優(yōu)化設(shè)計和計算使得優(yōu)化后的旋轉(zhuǎn)機架重量從240t降至162t，仍然能達到等中心精度要求。這是結(jié)構(gòu)優(yōu)化設(shè)計方法首次在旋轉(zhuǎn)機架設(shè)計的應(yīng)用，起到了非常好的效果，也將結(jié)果運用到后續(xù)的實際生產(chǎn)制造過程中，，是非常具有意義的研究工作。
[Abstract]:The proton therapy device is a new type of large medical equipment for curing tumors in the world. Among them, the rotating frame Gantrye has the characteristics of large structure and high precision. The Shanghai proton therapy demonstration device is the first fully independent development of proton therapy technology in China. Among them, a new type of rotary frame is a large precision mechanical structure with an angle of 180 degrees of rotation, a rotating radius of 5.4 m and a weight of 162 tons. As the first self-developed rotating frame in China, it aims at a new type of semi-rotating structure, which is currently being actively developed in the world. The structure and index parameters of the design body are in line with the international standard, and have the characteristics of large space, light weight, high performance-to-price ratio, etc. However, due to the lack of reference materials, the precision of the isocentric structure is very high, and the design of supporting buildings is complex. At the same time, it must have high performance and price ratio to adapt to market competition, so it is very difficult to design. This paper first introduces the general situation of proton therapy technology, and then systematically introduces the development of rotating frame in the world and some calculation and analysis in the period of trial and research. The purpose of this paper: in order to ensure that the structure of the rotating frame has high performance-price ratio, it is necessary to optimize the structure under the condition of ensuring precision in order to greatly reduce the overall weight and achieve the high quality and low price. Methods adopted: physical optimization, empirical design optimization, topology optimization and dimension optimization. The main theoretical basis of structural optimization design are topology optimization ESO finite element method, genetic algorithm and sequential quadratic programming algorithm in dimension optimization, experimental design method and response surface technology. The application of software and calculation process: SolidworksAnsys Optimus software is used to optimize the topology and size of the main parts respectively. The main optimization process and checking calculation of the structure are described in this paper. The result of optimization: through the optimization design and calculation of several main components, the weight of the optimized rotating rack can be reduced from 240 t to 162 t, and the accuracy of the rotation frame can still be achieved. This is the first application of the structural optimization design method in the design of the rotating rack. It has a very good effect, and it is a very meaningful research work to apply the results to the subsequent actual manufacturing process.
【學(xué)位授予單位】：中國科學(xué)院研究生院（上海應(yīng)用物理研究所）
【學(xué)位級別】：博士
【學(xué)位授予年份】：2015
【分類號】：TH774

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