本文關(guān)鍵詞： 全自動(dòng) 高精度 分液系統(tǒng) SoC　出處：《重慶大學(xué)》2016年碩士論文　論文類型：學(xué)位論文

【摘要】：分液系統(tǒng)被廣泛應(yīng)用于飲料分裝、食品生產(chǎn)、臨床醫(yī)療、生化實(shí)驗(yàn)、藥物研發(fā)等領(lǐng)域,尤其是在臨床醫(yī)療領(lǐng)域,需要采用高精度、無污染的微量分液設(shè)備進(jìn)行分液操作,以保證后續(xù)檢測(cè)結(jié)果的準(zhǔn)確性。我國微量分液系統(tǒng)產(chǎn)品較少,儀器的分液精度普遍不高、穩(wěn)定性較差;目前市場(chǎng)中主流的高精度分裝系統(tǒng)大多由國外企業(yè)制造生產(chǎn),其價(jià)格昂貴、體積較大。因此,自主研發(fā)一款小型化、低成本的微量高效分液系統(tǒng),具有較高的社會(huì)價(jià)值和經(jīng)濟(jì)效益。論文選用ARM+FPGA的SoC架構(gòu),設(shè)計(jì)了一款全自動(dòng)、高精度、無污染、多控制端的微量液體分裝系統(tǒng)。通過設(shè)計(jì)泵閥一體模塊,有效地提高了儀器的分液精度、降低了儀器的成本;通過設(shè)計(jì)電容式液面探測(cè)模塊,極大地減少了儀器在分液過程中出現(xiàn)的液體漏加、液體間交叉污染以及分液針掛液等現(xiàn)象,進(jìn)一步提高了儀器的分液精度;搭建SoC系統(tǒng),通過在FPGA資源中設(shè)計(jì)相應(yīng)的控制邏輯,實(shí)現(xiàn)對(duì)電機(jī)、傳感器等外設(shè)的驅(qū)動(dòng)控制;通過在HPS中移植Linux操作系統(tǒng)、Qt圖形界面開發(fā)庫以及SQLite輕量級(jí)數(shù)據(jù)庫,實(shí)現(xiàn)儀器主控軟件設(shè)計(jì);通過開發(fā)手機(jī)控制軟件對(duì)儀器進(jìn)行遠(yuǎn)程控制和信息管理,在對(duì)有毒有害液體的分液環(huán)境中,有效地保障了操作人員的人身安全。論文的主要貢獻(xiàn)有:(1)根據(jù)泵閥一體的實(shí)現(xiàn)原理,提出了分段補(bǔ)償?shù)姆椒?消除了因電機(jī)丟步和空氣壓縮帶來的分液誤差,提高了分液精度;(2)針對(duì)分液過程中存在交叉污染的問題,采用電容式傳感器作為信號(hào)來源,利用電容—占空比轉(zhuǎn)換方式實(shí)現(xiàn)了對(duì)液面的精準(zhǔn)探測(cè);(3)針對(duì)有毒、有害液體進(jìn)行分液時(shí)可能存在威脅操作員人身安全的問題,采用先進(jìn)的多終端控制方式,實(shí)現(xiàn)了對(duì)儀器的靈活控制。論文實(shí)現(xiàn)了微量高效的分液系統(tǒng)設(shè)計(jì),該系統(tǒng)包括儀器分液、洗滌、保養(yǎng)、多終端控制等多項(xiàng)功能,控制軟件結(jié)構(gòu)清晰、界面友好。經(jīng)反復(fù)測(cè)試驗(yàn)證,系統(tǒng)可達(dá)到450孔位/小時(shí)的分液速度、5ul的分液量級(jí)、99.6%的液面探測(cè)準(zhǔn)確度。達(dá)到了合作公司提出的要求。
[Abstract]:Liquid separation system is widely used in beverage packaging, food production, clinical medicine, biochemical experiments, drug development and other fields, especially in the field of clinical medicine, need to use high accuracy. In order to ensure the accuracy of the follow-up detection results, there are few products of the micro-liquid separation system in China, the accuracy of the instrument is generally low, and the stability of the instrument is poor. At present, most of the mainstream high-precision fractionation systems in the market are manufactured by foreign enterprises, which are expensive and large in volume. Therefore, a miniaturized and low-cost micro-high efficient liquid separation system has been developed independently. It has high social value and economic benefit. In this paper, ARM FPGA SoC framework is used to design a fully automatic, high-precision and pollution-free model. By designing the integral module of pump valve, the precision of liquid separation of the instrument is improved effectively, and the cost of the instrument is reduced. Through the design of capacitive liquid level detection module, the leakage of liquid, cross-contamination between liquids and the suspension of liquid needle in the separation process of the instrument are greatly reduced, and the precision of liquid separation is further improved. The SoC system is built, and the corresponding control logic is designed in the FPGA resource to realize the drive control of the motor, sensor and other peripheral devices. The design of instrument master control software is realized by transplanting Linux operating system QT graphical interface development library and SQLite lightweight database in HPS. Through the development of mobile phone control software for remote control of the instrument and information management in the toxic and harmful liquid separation environment. The main contribution of this paper is: 1) according to the realization principle of pump valve, the method of piecewise compensation is put forward. The separation error caused by motor step loss and air compression is eliminated, and the separation accuracy is improved. (2) aiming at the problem of cross contamination in liquid separation process, capacitive sensor is used as signal source and precise detection of liquid surface is realized by means of capacitance-duty cycle conversion. 3) aiming at the problem that the poisonous and harmful liquid may threaten the personal safety of the operator, the advanced multi-terminal control method is adopted. The paper realizes the design of micro-high efficient liquid separation system, which includes the functions of instrument separation, washing, maintenance, multi-terminal control and so on, and the control software structure is clear. The interface is friendly. After repeated test and verification, the system can reach the level detection accuracy of 99.6% of 450pore / hour liquid separation speed of 5ul, which meets the requirements of the cooperation company.
【學(xué)位授予單位】：重慶大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類號(hào)】：TH89

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本文編號(hào)：1473169