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全自動多通道高精度分液系統(tǒng)設計與實現(xiàn)

發(fā)布時間:2018-01-29 10:13

  本文關鍵詞: 全自動 高精度 分液系統(tǒng) SoC 出處:《重慶大學》2016年碩士論文 論文類型:學位論文


【摘要】:分液系統(tǒng)被廣泛應用于飲料分裝、食品生產、臨床醫(yī)療、生化實驗、藥物研發(fā)等領域,尤其是在臨床醫(yī)療領域,需要采用高精度、無污染的微量分液設備進行分液操作,以保證后續(xù)檢測結果的準確性。我國微量分液系統(tǒng)產品較少,儀器的分液精度普遍不高、穩(wěn)定性較差;目前市場中主流的高精度分裝系統(tǒng)大多由國外企業(yè)制造生產,其價格昂貴、體積較大。因此,自主研發(fā)一款小型化、低成本的微量高效分液系統(tǒng),具有較高的社會價值和經濟效益。論文選用ARM+FPGA的SoC架構,設計了一款全自動、高精度、無污染、多控制端的微量液體分裝系統(tǒng)。通過設計泵閥一體模塊,有效地提高了儀器的分液精度、降低了儀器的成本;通過設計電容式液面探測模塊,極大地減少了儀器在分液過程中出現(xiàn)的液體漏加、液體間交叉污染以及分液針掛液等現(xiàn)象,進一步提高了儀器的分液精度;搭建SoC系統(tǒng),通過在FPGA資源中設計相應的控制邏輯,實現(xiàn)對電機、傳感器等外設的驅動控制;通過在HPS中移植Linux操作系統(tǒng)、Qt圖形界面開發(fā)庫以及SQLite輕量級數(shù)據(jù)庫,實現(xiàn)儀器主控軟件設計;通過開發(fā)手機控制軟件對儀器進行遠程控制和信息管理,在對有毒有害液體的分液環(huán)境中,有效地保障了操作人員的人身安全。論文的主要貢獻有:(1)根據(jù)泵閥一體的實現(xiàn)原理,提出了分段補償?shù)姆椒?消除了因電機丟步和空氣壓縮帶來的分液誤差,提高了分液精度;(2)針對分液過程中存在交叉污染的問題,采用電容式傳感器作為信號來源,利用電容—占空比轉換方式實現(xiàn)了對液面的精準探測;(3)針對有毒、有害液體進行分液時可能存在威脅操作員人身安全的問題,采用先進的多終端控制方式,實現(xiàn)了對儀器的靈活控制。論文實現(xiàn)了微量高效的分液系統(tǒng)設計,該系統(tǒng)包括儀器分液、洗滌、保養(yǎng)、多終端控制等多項功能,控制軟件結構清晰、界面友好。經反復測試驗證,系統(tǒng)可達到450孔位/小時的分液速度、5ul的分液量級、99.6%的液面探測準確度。達到了合作公司提出的要求。
[Abstract]:Liquid separation system is widely used in beverage packaging, food production, clinical medicine, biochemical experiments, drug development and other fields, especially in the field of clinical medicine, need to use high accuracy. In order to ensure the accuracy of the follow-up detection results, there are few products of the micro-liquid separation system in China, the accuracy of the instrument is generally low, and the stability of the instrument is poor. At present, most of the mainstream high-precision fractionation systems in the market are manufactured by foreign enterprises, which are expensive and large in volume. Therefore, a miniaturized and low-cost micro-high efficient liquid separation system has been developed independently. It has high social value and economic benefit. In this paper, ARM FPGA SoC framework is used to design a fully automatic, high-precision and pollution-free model. By designing the integral module of pump valve, the precision of liquid separation of the instrument is improved effectively, and the cost of the instrument is reduced. Through the design of capacitive liquid level detection module, the leakage of liquid, cross-contamination between liquids and the suspension of liquid needle in the separation process of the instrument are greatly reduced, and the precision of liquid separation is further improved. The SoC system is built, and the corresponding control logic is designed in the FPGA resource to realize the drive control of the motor, sensor and other peripheral devices. The design of instrument master control software is realized by transplanting Linux operating system QT graphical interface development library and SQLite lightweight database in HPS. Through the development of mobile phone control software for remote control of the instrument and information management in the toxic and harmful liquid separation environment. The main contribution of this paper is: 1) according to the realization principle of pump valve, the method of piecewise compensation is put forward. The separation error caused by motor step loss and air compression is eliminated, and the separation accuracy is improved. (2) aiming at the problem of cross contamination in liquid separation process, capacitive sensor is used as signal source and precise detection of liquid surface is realized by means of capacitance-duty cycle conversion. 3) aiming at the problem that the poisonous and harmful liquid may threaten the personal safety of the operator, the advanced multi-terminal control method is adopted. The paper realizes the design of micro-high efficient liquid separation system, which includes the functions of instrument separation, washing, maintenance, multi-terminal control and so on, and the control software structure is clear. The interface is friendly. After repeated test and verification, the system can reach the level detection accuracy of 99.6% of 450pore / hour liquid separation speed of 5ul, which meets the requirements of the cooperation company.
【學位授予單位】:重慶大學
【學位級別】:碩士
【學位授予年份】:2016
【分類號】:TH89

【參考文獻】

相關期刊論文 前10條

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