【摘要】：病理組織處理是對患者的病變組織進行提取和處理的過程,通過觀察研究組織細胞形態(tài)結構和變化情況,判斷細胞病變、轉移和擴散程度。病理組織的處理需要經過細胞固定、浸蠟、組織細胞處理、制作切片和染色等流程。組織細胞的處理是病理組織處理不可或缺的環(huán)節(jié)。超聲功放用于對組織細胞的處理,是快速病理組織產品的核心部分,決定組織細胞處理的質量和速度,對患者的治療有著直接的影響�？焖俨±斫M織可以節(jié)約臨床上組織細胞檢查的時間并應用于醫(yī)院大規(guī)模的癌癥的檢查篩選。由于絕大多數(shù)的病理處理產品是國外公司研發(fā)的,國內從事開發(fā)此類產品的公司相對較少,導致國內市場上病理組織的產品比較缺乏。醫(yī)院從國外購買設備價格昂貴,維修成本高。課題是在這樣的背景下進行確立的,對快速病理組織產品核的超聲功放進行研究,目的是要研制出一款高效穩(wěn)定的超聲功率放大器。超聲功率放大器是應用型的研究課題,因此,在產品的具體設計的過程中考慮了企業(yè)需求。超聲功率放大器劃分多個模塊并分別設計,主要包括信號源電路、驅動電路、負載電路、隔離電路和電源。本文重點研究以下幾個方面:第一、論文緒論部分闡述了超聲功率放大器的產生背景和研究意義,總結超聲功率放大器的發(fā)展過程和趨勢。分析了當前超聲功率放大器情況,制定論文的工作計劃。第二、介紹超聲功率放大器的概念和工作的流程,簡述半橋和全橋工作原理,比較了兩種工作模式的優(yōu)缺點。第三、重點介紹超聲功率放大器的電路原理和設計,主要包括信號源芯片、驅動芯片和MOSFET管的選擇。分析了全橋電路的原理、驅動芯片的典型電路和電路的優(yōu)化設計,解決了在課題研究過程中發(fā)現(xiàn)的問題。第四、介紹了STM32芯片的系統(tǒng)組成,詳細介紹了時鐘樹和定時器的理論知識,軟件開發(fā)平臺的介紹和配置步驟,程序編寫的思路和程序的初始化,信號的下載和調試。第五、介紹了電路板制作、調試和總結展望,包括在電路板設計過程中器件選型、電路的布局,電源線和信號線的布線規(guī)則。對超聲功率放大器進行系統(tǒng)調試,并展示部分調試結果�？偨Y已經完成的工作,提出了超聲功率放大器需要改進的地方和展望。
[Abstract]:Pathological tissue processing is the process of extracting and treating the pathological tissues of patients. The degree of cytopathology, metastasis and diffusion is judged by observing and studying the morphological structure and changes of tissues. The treatment of pathological tissue involves cell fixation, wax immersion, tissue cell processing, section making and staining. The treatment of histocytes is an indispensable link in the treatment of pathological tissues. Ultrasonic power amplifier is the core part of the rapid pathological tissue product, which determines the quality and speed of tissue cell processing, and has a direct impact on the treatment of patients. Rapid histopathology can save time for clinical histocyte examination and can be used for screening large-scale cancer in hospitals. Because most of the pathological products are developed by foreign companies, the number of domestic companies engaged in the development of such products is relatively few, resulting in the lack of pathological products in the domestic market. The hospital buys the equipment from the foreign expensive, the maintenance cost is high. Under this background, this paper studies the ultrasonic power amplifier of the rapid pathological tissue nuclear. The purpose is to develop a high efficient and stable ultrasonic power amplifier. Ultrasonic power amplifier is an applied research subject. Therefore, the demand of enterprise is considered in the process of product design. The ultrasonic power amplifier is divided into several modules, including signal source circuit, drive circuit, load circuit, isolation circuit and power supply. This paper focuses on the following aspects: first, the introduction of the paper describes the background and research significance of ultrasonic power amplifier, summarizes the development process and trend of ultrasonic power amplifier. The current situation of ultrasonic power amplifier is analyzed, and the work plan of the thesis is worked out. Secondly, the concept and working flow of ultrasonic power amplifier are introduced. The principle of half bridge and full bridge are briefly described, and the advantages and disadvantages of the two modes are compared. Thirdly, the circuit principle and design of ultrasonic power amplifier are introduced, including signal source chip, driver chip and MOSFET transistor. The principle of the full bridge circuit, the typical circuit of the drive chip and the optimum design of the circuit are analyzed, and the problems found in the course of the research are solved. Fourthly, the system composition of STM32 chip is introduced, the theoretical knowledge of clock tree and timer, the introduction and configuration steps of software development platform, the train of thought of programming and the initialization of program, the downloading and debugging of signal are introduced in detail. Fifthly, it introduces the circuit board making, debugging and summing up prospect, including device selection, circuit layout, wiring rules of power cord and signal wire in the process of circuit board design. The system of ultrasonic power amplifier is debugged, and some debugging results are shown. The work done is summarized, and the improvement of ultrasonic power amplifier is put forward.
【學位授予單位】：山東師范大學
【學位級別】：碩士
【學位授予年份】：2017
【分類號】：TN722.75

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