本文選題：無酶電化學(xué)傳感器 + 電化學(xué)發(fā)光��； 參考：《東北師范大學(xué)》2015年碩士論文

【摘要】：電化學(xué)傳感器是目前生命科學(xué)及臨床醫(yī)學(xué)測試方法研究中最為活躍的領(lǐng)域之一,已廣泛用于臨床、工業(yè)、環(huán)境和農(nóng)業(yè)分析等領(lǐng)域。納米科學(xué)的出現(xiàn)、生長以及成熟,為電化學(xué)傳感器的發(fā)展提供了很好的前提條件。最近幾年,基于納米材料比表面積大、表面反應(yīng)活性高、電催化能力強等特性,越來越多的人們使用無酶電化學(xué)和電致發(fā)光技術(shù),構(gòu)建能夠?qū)﹄p氧水,葡萄糖等物質(zhì)進(jìn)行檢測的新型無酶電化學(xué)傳感器。本論文基于納米復(fù)合材料的優(yōu)越性和電化學(xué)傳感技術(shù)的靈敏性,構(gòu)建了電化學(xué)性能優(yōu)良的葡萄糖和過氧化氫新型電化學(xué)傳感器,拓寬了電化學(xué)傳感器的應(yīng)用領(lǐng)域,具體內(nèi)容如下:1.提出了一種基于鈣鈦礦型納米復(fù)合材料(La Ti O3-Ag0.1)的新型無酶電化學(xué)發(fā)光葡萄糖傳感器(La Ti O3-Ag0.1-modified-GCE)。用溶膠-凝膠的合成方法制備了La Ti O3-Ag0.1納米復(fù)合材料,并采用一系列表征手段(SEM、TEM、XRD)和電化學(xué)測定方法對其形貌和電化學(xué)性能進(jìn)行了研究。在最優(yōu)化的實驗條件下,測試了此傳感器對葡萄糖檢測的線性范圍和檢測限,并進(jìn)一步研究了其實際應(yīng)用性。2.研究了一種無酶電化學(xué)發(fā)光葡萄糖傳感器(Au-HS/SO3H-PMO(Et)-modified GCE),這種能化納米復(fù)合材料(Au-HS/SO3H-PMO(Et))以功能化有序介孔硅(HS/SO3H-PMO(Et))為載體,通過共價鍵作用將金納米顆粒摻雜到有序介孔硅中。利用Au納米顆粒好的電催化活性,實現(xiàn)了對葡萄糖的電催化氧化。3.研制出一種基于功能化納米復(fù)合材料(Au-HS/SO3H-PMO(Et))的新型無酶過氧化氫傳感器(Au-HS/SO3H-PMO(Et)-modified GCE),通過一系列的電化學(xué)測試手段,對修飾電極的電化學(xué)行為進(jìn)行了考察,在最佳條件下,此傳感器對過氧化氫的檢測表現(xiàn)出了好的響應(yīng)特性:高的靈敏度、低的檢測限、寬的線性范圍、好的選擇性以及令人滿意的實際應(yīng)用性。4.構(gòu)建了一種基于高醇羥基硝酸氧鉍(HO-Bi ONO3)納米復(fù)合材料的新型無酶葡萄糖傳感器(HO-Bi ONO3-modified GCE)。應(yīng)用一系列表征手段和電化學(xué)測試技術(shù),對HO-Bi ONO3納米復(fù)合材料的形貌、組成以及修飾電極對過氧化氫的檢測進(jìn)行了研究,并將其進(jìn)一步應(yīng)用于實際血樣中葡萄糖的檢測。
[Abstract]:Electrochemical sensor is one of the most active fields in the research of life science and clinical medicine testing methods. It has been widely used in the fields of clinical, industrial, environmental and agricultural analysis. The appearance, growth and maturity of nanoscience have provided a good premise for the development of electrochemical sensors. In recent years, the ratio of nano materials to nano materials is based on the ratio of nano materials. Large surface area, high surface reactivity, strong electrocatalysis ability and so on. More and more people use non enzyme electrochemistry and electroluminescent technology to construct a new non enzyme electrochemical sensor which can detect hydrogen peroxide and glucose. This paper is based on the advantages of nanocomposites and the sensitivity of electrochemical sensing technology. A new electrochemical biosensor with excellent electrochemical performance for glucose and hydrogen peroxide has been constructed, which widens the application field of electrochemical sensors. The specific contents are as follows: 1. a novel non enzyme electrochemiluminescence glucose sensor (La Ti O3-Ag0.1-modified-GCE) based on the perovskite nano composite material (La Ti O3-Ag0.1) is proposed. La Ti O3-Ag0.1 nanocomposites were prepared by the synthetic method of gel gel. The morphology and electrochemical properties of the nanocomposites were studied by a series of characterization methods (SEM, TEM, XRD) and electrochemical methods. The linear range and detection limit of the sensor on the detection of grape sugar were tested under the optimal experimental conditions. Its practical application.2. has studied an enzyme free electrochemiluminescence glucose sensor (Au-HS/SO3H-PMO (Et) -modified GCE). This energetic nanocomposite (Au-HS/SO3H-PMO (Et)) is supported by functional ordered mesoporous Kong Gui (Et). Gold nanoparticles are doped into the ordered mesoporous silica through the covalent bond, and Au nanoscale is used. A new type of non enzyme hydrogen peroxide sensor (Au-HS/SO3H-PMO (Et) -modified GCE) based on functionalized nano composite material (Au-HS/SO3H-PMO (Et)) was developed for the electrocatalytic oxidation of glucose. The electrochemical behavior of the modified electrode was investigated by a series of electrochemical testing methods, and the electrochemical behavior of the modified electrode was investigated. The electrochemical behavior of the modified electrode was investigated by a series of electrochemical testing methods. Under optimal conditions, the sensor has good response characteristics to the detection of hydrogen peroxide: high sensitivity, low detection limit, wide linear range, good selectivity and satisfactory practical application.4., a novel enzyme free glucose sensor based on HO-Bi ONO3 nanocomposite (HO) nanocomposite (HO) is constructed. -Bi ONO3-modified GCE). Using a series of characterization methods and electrochemical testing techniques, the morphology and composition of HO-Bi ONO3 nanocomposites and the detection of hydrogen peroxide by modified electrode were studied, and it was further applied to the detection of glucose in the actual blood samples.
【學(xué)位授予單位】：東北師范大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：TB33;O657.1

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