本文選題：多孔有機(jī)骨架材料 + 熒光和比色傳感�。� 參考：《山西師范大學(xué)》2017年碩士論文

【摘要】：近年來(lái),化學(xué)傳感器由于使用方便,靈敏度高、選擇性好、響應(yīng)迅速、操作簡(jiǎn)單等優(yōu)點(diǎn),在化學(xué)、生物、醫(yī)學(xué)和環(huán)境等諸多領(lǐng)域有著潛在的應(yīng)用價(jià)值。多孔有機(jī)骨架材料POFs憑借其高的比表面積、高的穩(wěn)定性和可修飾性等特點(diǎn)在熒光傳感領(lǐng)域的應(yīng)用也受到人們的廣泛關(guān)注。本論文主要研究了咔唑基多孔材料及希夫堿有機(jī)骨架材料在離子傳感和生物傳感領(lǐng)域的應(yīng)用,主要分為四部分:第一章首先簡(jiǎn)要介紹了熒光和化學(xué)傳感器,然后綜述了多孔有機(jī)骨架作為熒光傳感器的研究進(jìn)展。最后對(duì)本論文的選題意義及研究所取得的進(jìn)展進(jìn)行了描述。第二章通過(guò)三氯化鐵氧化偶聯(lián)成功合成了具有四面體結(jié)構(gòu)的三維有機(jī)骨架材料Cz-TPM及共軛結(jié)構(gòu)的有機(jī)骨架材料Cz-BCB。Cz-TPM由于具有大量的富電子咔唑基團(tuán)和對(duì)客體分子的高密度結(jié)合位點(diǎn),我們對(duì)其I-和Hg2識(shí)別性能進(jìn)行研究。研究表明Cz-TPM可實(shí)現(xiàn)對(duì)I-和Hg2+的可視化和熒光識(shí)別。I-的加入使Cz-TPM分散液的外觀顏色由無(wú)色變?yōu)辄S色,緊接著加入Hg2+使分散液的顏色由黃色恢復(fù)到無(wú)色。熒光檢測(cè)表明Cz-TPM對(duì)I-具有專(zhuān)一選擇性,成功實(shí)現(xiàn)了對(duì)I-的turn-off光學(xué)識(shí)別響應(yīng)(猝滅常數(shù)Ksv[I-]:2372M-1),隨后在Cz-TPM@I體系中加入Hg2+,實(shí)現(xiàn)了對(duì)Hg2+專(zhuān)一靈敏的turn-on模式光學(xué)響應(yīng)。更重要的是,Cz-TPM具有優(yōu)異的溶劑穩(wěn)定性,通過(guò)水洗和離心分離就能使其再生并重復(fù)使用。據(jù)我們所知,這是首例有關(guān)咔唑多孔有機(jī)骨架對(duì)I-和Hg2+的熒光傳感的報(bào)道。緊接著我們研究了具有共軛結(jié)構(gòu)的有機(jī)骨架材料Cz-BCB對(duì)I-和Hg2+的可視化和熒光傳感性能,發(fā)現(xiàn)由于Cz-BCB中存在大的π-共軛體系使其對(duì)I-和Hg2+傳感效果更靈敏(猝滅常數(shù)Ksv[I-]:4611M-1);同時(shí),Cz-BCB對(duì)Fe2+的識(shí)別具有高靈敏性和抗干擾性,檢測(cè)限可達(dá)到0.46μM。第三章在溶劑熱的條件下通過(guò)縮合反應(yīng)制備了具有酮式結(jié)構(gòu)COF-JLU2。COF-JLU2骨架中特殊的結(jié)構(gòu),以及良好的化學(xué)穩(wěn)定性和熱穩(wěn)定性,促使我們嘗試?yán)肅OF-JLU2對(duì)金屬離子,pH值以及核苷酸堿基進(jìn)行熒光識(shí)別。研究表明COF-JLU2可選擇性熒光識(shí)別Al3+(turn-on型),Al3+檢測(cè)限達(dá)到0.31μM;此外,pH的變化使COF-JLU2發(fā)生質(zhì)子化與去質(zhì)子化,熒光強(qiáng)度及外觀顏色都會(huì)發(fā)生改變,因而可實(shí)現(xiàn)對(duì)pH值的檢測(cè);COF-JLU2骨架中的氫鍵的給體-給體-受體(DDA)部分與胞嘧啶分子中(AAD)部分互補(bǔ),因而對(duì)胞嘧啶具有很好的熒光傳感效果。第四章對(duì)本論文的主要工作進(jìn)行了總結(jié)并對(duì)該課題的研究前景進(jìn)行展望。
[Abstract]:In recent years, chemical sensors have been widely used in many fields, such as chemistry, biology, medicine and environment, because of their advantages such as convenient use, high sensitivity, good selectivity, quick response and simple operation. Because of its high specific surface area, high stability and modifiability, porous organic skeleton material POFs has been widely used in the field of fluorescence sensing. The applications of carbazolyl porous materials and Schiff base organic skeleton materials in the field of ion sensing and biosensor are mainly studied in this paper. The first chapter briefly introduces the fluorescent and chemical sensors. Then the research progress of porous organic skeleton as fluorescence sensor is reviewed. Finally, the significance of the topic and the progress of the research are described. In chapter 2, the three-dimensional organic skeleton material Cz-TPM with tetrahedron structure and the organic skeleton material Cz-BCB.Cz-TPM with conjugated structure have been successfully synthesized by oxidative coupling of ferric trichloride with a large number of electron-rich carbazole groups and high density binding sites to guest molecules. We study its I-and Hg2 recognition performance. The results show that Cz-TPM can realize the visualization of I- and Hg2 and the addition of fluorescence recognition. I- can change the appearance color of Cz-TPM dispersion from colorless to yellow, and then add Hg2 to restore the color of dispersion from yellow to colorless. Fluorescence detection shows that Cz-TPM is specific to I-, and the turn-off optical recognition response to I- (quenching constant Ksv [I-] 2372M-1) has been successfully realized. Subsequently, Hg2 was added to the Cz-TPM@I system to achieve a specific and sensitive turn-on mode optical response to Hg2. More importantly, Cz-TPM has excellent solvent stability, which can be regenerated and reused by washing and centrifugal separation. To the best of our knowledge, this is the first report on the fluorescence sensing of I-and Hg2 by a carbazole porous organic skeleton. Then we studied the visualization and fluorescence sensing properties of Cz-BCB, an organic skeleton material with conjugated structure, to I- and Hg2. It is found that the large 蟺 -conjugated system in Cz-BCB makes the sensing effect more sensitive to I- and Hg2 (quenching constant Ksv [I-] 4611M-1H, and Cz-BCB has high sensitivity and anti-interference to Fe2, and the detection limit can reach 0.46 渭 M. In chapter 3, the special structure, chemical stability and thermal stability of keto-type COF-JLU2.COF-JLU2 skeleton were prepared by condensation reaction under solvothermal conditions. We try to use COF-JLU2 to recognize pH value and nucleotide base of metal ions. The results showed that the detection limit of Al3 turn-on type Al3 in COF-JLU2 was 0.31 渭 M. in addition, the change of pH value made COF-JLU2 protonation and deprotonation, and the fluorescence intensity and appearance color would change. Therefore, the hydrogen donor-acceptor DDAs in the framework of COF-JLU2 can be detected by pH, which is complementary to the AAD in cytosine molecules, so it has a good fluorescence sensing effect on cytosine. The fourth chapter summarizes the main work of this paper and prospects for the research of this topic.
【學(xué)位授予單位】：山西師范大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類(lèi)號(hào)】：TB383.4;TP212

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相關(guān)期刊論文 前1條

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本文編號(hào)：1939708