發(fā)布時間：2018-04-23 12:12

  本文選題：水熱法 + 模板　； 參考：《中北大學》2015年碩士論文

【摘要】：具有特殊形貌和特殊結(jié)構(gòu)的中空微球材料近年來備受人們關(guān)注。相比于實心微球材料，中空微球由于內(nèi)部具有空腔結(jié)構(gòu)而表現(xiàn)出低密度、高比表面積且可以容納客體分子等特點，因此在生物醫(yī)藥、涂料、電子、催化、分離等眾多領(lǐng)域有著廣闊的應用前景。隨著中空微球的特殊功能逐漸為人們所認識，對其制備方法的研究也日益深入。目前，制備中空微球的方法主要有乳液法、懸浮法、溶脹法、模板法、自組裝法、沉積法等[1]。不同的制備方法能夠制備出不同材料、不同結(jié)構(gòu)和不同尺度的中空微球。如不同材質(zhì)的中空微球包括：聚合物/無機復合材料、無機材料、有機高分子材料中空微球。本論文分別通過采用一步水熱和聚合物(PS)作為模板來制備PEG@Gd2O3:Tb3+，中空介孔Gd2O3:Eu3+微球和PANI@ERGO復合中空微球，分別對其藥物緩釋性能及電化學性能分別進行了系統(tǒng)全面的研究。主要研究結(jié)果總結(jié)如下: 1、采用一步水熱法制備出了復合中空PEG@Gd2O3:Tb3+微球。通過XRD、TEM、PL等進行了表征。對其形成機理和藥物緩釋性能也進行了分析。獲得的復合中空PEG@Gd2O3:Tb3+微球載藥量可達261.5mg/g，緩釋時間為24h。藥物緩釋性能結(jié)果表明，復合微球具有較高的載藥量及較長的藥物緩釋時間。 2、利用羧基化聚苯乙烯微球(CCPS)作為模板利用尿素沉淀，再通過煅燒法制備出了中空介孔Gd2O3:Eu3+微球，，其XRD中的峰值與純的立方相的Gd2O3一致。透射電子顯微鏡和掃描電子顯微鏡圖像表明，中空介孔微球的平均直徑約276nm，殼層的厚度約22nm。載藥量達189.7mg/g，藥物緩釋時間達60h。 3、通過以聚苯乙烯(PS)微球作為模板，通過溶脹和超聲輻照成功的制備出了PANI@ERGO復合中空微球。通過XRD、SEM、TEM、電化學工作站等對產(chǎn)物的形成、形態(tài)及電化學性能進行了表征。電化學性能測試結(jié)果表明，復合中空微球具有較好的電化學性能，在500次循環(huán)后，保留了首次放電容量的92.02%，電容量為604F/g。
[Abstract]:Hollow microspheres with special morphology and special structure have attracted much attention in recent years. Compared with solid microspheres, hollow microspheres exhibit the characteristics of low density, high specific surface area and ability to accommodate guest molecules because of their cavity structure. Therefore, hollow microspheres are widely used in biomedicine, coatings, electronics, catalysis, and so on. Separation and many other fields have broad application prospects. As the special function of hollow microspheres has been gradually recognized, the preparation of hollow microspheres has been studied more and more deeply. At present, the main methods of preparing hollow microspheres are emulsion method, suspension method, swelling method, template method, self-assembly method, deposition method and so on [1]. The hollow microspheres with different materials, structures and sizes can be prepared by different preparation methods. For example, hollow microspheres of different materials include: polymer / inorganic composites, inorganic materials, organic polymer hollow microspheres. In this paper, PEG@Gd2O3:Tb3 was prepared by using one-step hydrothermal and polymer PS as templates, hollow mesoporous Gd2O3:Eu3 microspheres and PANI@ERGO composite hollow microspheres were prepared respectively. The drug slow-release properties and electrochemical properties of the microspheres were systematically and comprehensively studied. The main findings are summarized as follows: 1. The composite hollow PEG@Gd2O3:Tb3 microspheres were prepared by one step hydrothermal method. It was characterized by XRDX Tem PL and so on. The formation mechanism and drug release properties were also analyzed. The drug loading of the composite hollow PEG@Gd2O3:Tb3 microspheres was 261.5 mg / g and the sustained release time was 24 h. The results showed that the composite microspheres had higher drug loading and longer drug release time. 2. The hollow mesoporous Gd2O3:Eu3 microspheres were prepared using carboxylated polystyrene microspheres (CCPs) as template and urea precipitation. The peak value of the hollow mesoporous Gd2O3:Eu3 microspheres was the same as that of pure cubic Gd2O3. Transmission electron microscopy (TEM) and scanning electron microscopy (SEM) images show that the average diameter of hollow mesoporous microspheres is about 276 nm and the thickness of shell is about 22 nm. The drug load was 189.7 mg / g and the drug release time was 60 h. 3. PANI@ERGO composite hollow microspheres were successfully prepared by swelling and ultrasonic irradiation using polystyrene (PS) microspheres as template. The formation, morphology and electrochemical properties of the products were characterized by XRDX SEMM-TEM and electrochemical workstation. The electrochemical performance test results show that the composite hollow microspheres have good electrochemical performance. After 500 cycles, the initial discharge capacity of the composite hollow microspheres is 92.02 and the capacitance is 604F / g.
【學位授予單位】：中北大學
【學位級別】：碩士
【學位授予年份】：2015
【分類號】：TB34;O646

【參考文獻】

相關(guān)期刊論文 前1條

1 鄧偉;宮理想;程冠之;闞成友;;中空微球及其制備方法[J];高分子通報;2011年04期

本文編號：1791926