本文選題：膠體晶體 + pH-響應(yīng)��； 參考：《青島大學(xué)》2017年碩士論文

【摘要】：聚合物微球較其他材料相比,因具有獨(dú)特的物理、化學(xué)性能,近年來(lái)被廣泛應(yīng)用于光子晶體、藥物靶向輸送載體、催化劑、環(huán)境保護(hù)材料以及仿生材料等領(lǐng)域。膠體晶體是近年來(lái)比較熱門(mén)的一種新興材料,是制備光子晶體、特異性傳感器等的重要方法。膠體晶體最直觀的特點(diǎn)就是其具有絢麗的結(jié)構(gòu)顏色,如何將其成功的應(yīng)用于制備直觀的傳感器,是目前學(xué)術(shù)界的研究重點(diǎn)。微米級(jí)單分散多孔聚合物微球主要被應(yīng)用于液相色譜柱填料,制備不同材料、性能的色譜柱填料,是未來(lái)科技發(fā)展的重中之重。本論文通過(guò)對(duì)無(wú)皂乳液聚合制備聚苯乙烯乳膠顆粒的方法進(jìn)行改進(jìn),制備出具有pH響應(yīng)性能的單分散納米聚合物微球,并利用氣液界面組裝法制備出二維膠體晶體,并與原來(lái)制備的聚苯乙烯乳膠顆粒組裝形成的膠體晶體對(duì)比,發(fā)現(xiàn)該膠體晶體具有較好的pH響應(yīng)性能,并成功的將其應(yīng)用于酸性溶液的檢測(cè)。運(yùn)用改進(jìn)的兩步種子聚合法以微米級(jí)單分散聚甲基丙烯酸甲酯微球(PMMA)作為種子成功的制備出尺寸約2.5μm的單分散聚甲基丙烯酸甲酯交聯(lián)多孔微球,通過(guò)調(diào)整不同的致孔劑體系,能夠得出具有多種不同表面形貌的單分散多孔微球,且以甲苯:DBP=1:1致孔劑體系下得到的微球的孔隙最小,比表面積最大,是用作液相色譜柱填料的理想材料。并將其用作色譜柱填料,能夠成功的完成對(duì)精氨酸、甘氨酸和谷氨酸的分離,且分離效果佳,是運(yùn)用液相色譜分離氨基酸的新材料。除此之外,還通過(guò)乳液聚合和無(wú)皂乳液聚合制備出單分散乳膠粒,在酸/堿處理后得到表面含有豐富羧基的多孔乳膠粒。在接下來(lái)的研究中,充分利用多孔乳膠粒表面羧基,擬制備出各種功能化膠體晶體傳感器。本論文所研究的pH響應(yīng)型膠體晶體具備了可通過(guò)肉眼直觀的觀察溶液pH的差異,對(duì)酸堿條件下形成的膠體晶體的結(jié)構(gòu)發(fā)生明顯變化,可應(yīng)用于膠體晶體酸堿傳感器。所研究的單分散多孔PMMA交聯(lián)微球在作為色譜柱填料在分離蛋白質(zhì)和氨基酸等方面具有一定的應(yīng)用前景。以酸堿處理法制備多孔乳膠粒,功能化改性后組裝智能響應(yīng)膠體晶體傳感器,具有較大的應(yīng)用前景。
[Abstract]:Compared with other materials, polymer microspheres have been widely used in the fields of photonic crystals, drug targeting carriers, catalysts, environmental protection materials and bionic materials due to their unique physical and chemical properties.Colloidal crystal is a popular new material in recent years. It is an important method to prepare photonic crystals and specific sensors.The most intuitive feature of colloidal crystals is that they have brilliant structural colors. How to successfully apply them to the fabrication of intuitive sensors is the focus of academic research at present.Micron size monodisperse porous polymer microspheres are mainly used in liquid chromatographic column fillers to prepare chromatographic column fillers with different materials and properties, which are the most important in the development of science and technology in the future.In this paper, the method of preparing polystyrene latex particles by soap-free emulsion polymerization was improved to prepare monodisperse nano-polymer microspheres with pH response, and two-dimensional colloidal crystals were prepared by gas-liquid interface assembly method.Compared with the colloidal crystal assembled from the original polystyrene latex particles, it was found that the colloidal crystal had better pH response and was successfully applied to the detection of acidic solution.The modified two-step seed polymerization method was used to prepare the monodisperse polymethyl methacrylate crosslinked porous microspheres with the size of 2.5 渭 m by using micron size monodisperse polymethyl methacrylate microspheres (PMMA) as seeds. Different pore-forming agent systems were adjusted.The single dispersed porous microspheres with different surface morphologies can be obtained, and the microspheres with toluene: DBP 1: 1 pore-forming agent system have the smallest porosity and the largest specific surface area. It is an ideal material for liquid chromatographic column packing.The separation of arginine, glycine and glutamate can be successfully completed by using it as a column filler, and it is a new material for separation of amino acids by liquid chromatography.In addition, monodisperse latex particles were prepared by emulsion polymerization and soap-free emulsion polymerization. After acid / alkali treatment, porous latex particles with rich carboxyl groups were obtained.In the following studies, various functional colloidal crystal sensors were prepared by making full use of the carboxyl groups on the surface of porous latex particles.The pH-responsive colloidal crystals studied in this paper have obvious changes in structure of colloidal crystals formed under acid-base conditions, and can be used as acid-base sensors in colloidal crystals.The monodisperse porous PMMA crosslinked microspheres have a certain application prospect in separation of protein and amino acids as chromatographic column fillers.The porous latex particles were prepared by acid-base treatment and the intelligent response colloidal crystal sensor was assembled after functionalized modification.
【學(xué)位授予單位】：青島大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：TQ317;TB383.1

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本文編號(hào)：1764208