本文選題：電阻-脈沖分析方法　切入點(diǎn)：石英納米通道　出處：《電化學(xué)》2017年02期

【摘要】：本文報(bào)告了用于檢測單囊泡及其粒徑分析的石英納米通道電阻-脈沖分析方法.采用圓柱形石英納米通道可檢測粒徑為100~300 nm的單磷脂囊泡和直徑為170~400 nm的聚苯乙烯納米顆粒.單囊泡和納米顆粒的遷移可通過檢測各自產(chǎn)生的方波電流脈沖信號,并由此確定顆粒尺寸.結(jié)果表明,采用石英納米通道電阻-脈沖分析方法得到的顆粒/囊泡粒徑與采用動(dòng)態(tài)光散射法和掃描電子顯微法得到的結(jié)果完全一致.這種基于電子的分析方法具有快速簡單的特點(diǎn),所用的自制微傳感器廉價(jià)耐用.石英通道的應(yīng)用還可與其它分析方法如電流分析法和熒光顯微法聯(lián)用,以獲得生物囊泡及人工囊泡更完全的信息.
[Abstract]:A quartz nanochannel resistance - pulse analysis method for the detection of single vesicles and their particle size has been reported . Single - phospholipid vesicles with particle size of 100 - 300 nm and polystyrene nanoparticles with diameters of 170 - 400 nm can be detected by cylindrical quartz nano - channels . The particle size is determined by detecting the square - wave current pulse signals generated respectively . The results show that the particle size and particle size obtained by using the method of dynamic light scattering and scanning electron microscopy are quite consistent . The application of the quartz channel can also be combined with other analytical methods such as current analysis and fluorescence microscopy to obtain more complete information about the biological vesicles and artificial vesicles .

【作者單位】： 美國華盛頓大學(xué)化學(xué)系;
【基金】：financial supports from the National Institutes of Health(GM101133) the University of Washington
【分類號】：O657.1;TB383.1

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本文編號：1684564