2006-2015年醫(yī)院流感嗜血菌分布及耐藥性分析
[Abstract]:Objective to investigate the clinical distribution and antibiotic resistance of Haemophilus influenzae, and to provide evidence for rational selection of antibiotics. Methods from January 2006 to December 2015, the distribution of Haemophilus influenzae, the identification of strains and the results of drug sensitivity, the results of drug sensitivity test and the phenotypic analysis of drug resistance were analyzed by WHONET 5.6 software. Results 1671 strains of Haemophilus influenzae were isolated from the patients, and 1442 strains of Haemophilus influenzae were mainly from sputum (86.3%). The results of drug sensitivity showed that the sensitivity rate of Haemophilus influenzae to sulfamethoxazole / trimethoprim was 33.8% and 47.1%, followed by ampicillin 46.7% and 65.4%, respectively. The sensitivity rate to other antibiotics was high (70.0%). Conclusion the Haemophilus influenzae isolated in hospital mainly comes from respiratory tract specimens. Sulfamethoxazole / trimethoprim and ampicillin are no longer suitable for the empirical treatment of Haemophilus influenzae infection. Doctors should choose antibiotics reasonably according to the results of drug sensitivity.
【作者單位】: 華中科技大學(xué)同濟(jì)醫(yī)學(xué)院附屬同濟(jì)醫(yī)院檢驗(yàn)科;華中科技大學(xué)同濟(jì)醫(yī)學(xué)院附屬同濟(jì)醫(yī)院藥劑科;
【基金】:國(guó)家科技重大專(zhuān)項(xiàng)課題(2012ZX10004207)
【分類(lèi)號(hào)】:R446.5
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