【摘要】：目的 研究婦女生殖道B群鏈球菌(GBS)的檢出率及藥物敏感性分析。方法 對溫州醫(yī)科大學(xué)附屬第一醫(yī)院5115例婦女生殖道標(biāo)本進行病原菌培養(yǎng),重點對檢到的B群鏈球菌進行藥物敏感性試驗及對該標(biāo)本相應(yīng)陰道分泌物進行分析。結(jié)果 5115例婦女生殖道標(biāo)本中共培養(yǎng)B群鏈球菌180株,檢出率為3.52%(180/5115例)。180株B群鏈球菌對萬古霉素、替考拉寧、奎奴/達福普汀、替加環(huán)素、氨芐西林、青霉素的敏感率均為100.00%(180/180例),對呋喃妥因的敏感率為92.22%(166/180例),對莫西沙星的敏感率為82.22%(148/180例),對左氧氟沙星的敏感率為81.11%(146/180例),對環(huán)丙沙星的敏感率為55.00%(99/180例),對紅霉素的敏感率為22.22%(40/180例),對克林霉素的敏感率為10.00%(18/180例),對四環(huán)素的敏感率為7.78%(14/180例)。攜帶B群鏈球菌的婦女陰道分泌物的常規(guī)檢測的結(jié)果顯示,陰道分泌物p H值以p H4.40為主,為77.78%(140/180例);清潔度以Ⅲ度為主,為54.44%(98/180例)、Ⅳ度為17.78%(32/180例);滴蟲為5.56%(10/180例),真菌為12.22%(22/180例),線索細胞為8.89%(16/180例),唾液酸苷酶陽性率為13.33%(24/180例),過氧化氫陽性率為98.89%(178/180例),白細胞酯酶陽性率為95.56%(172/180例)。結(jié)論 婦女生殖道B群鏈球菌攜帶率相對較低,B群鏈球菌對常用抗菌藥物敏感性較高,攜帶B群鏈球菌婦女基本上具有陰道炎癥反應(yīng)。
[Abstract]:Objective to study the detection rate and drug sensitivity of group B streptococcus (GBS) in female genital tract. Methods 5115 female genital tract specimens were cultured in the first affiliated Hospital of Wenzhou Medical University. The drug sensitivity test of group B streptococcus and the analysis of vaginal secretions were carried out. Results 5115 female genital tract specimens were collected and the positive rate of Streptococcus group B was 3.52% (180 / 5115 cases). The results showed that 5115 strains of Streptococcus group B were resistant to vancomycin, teicoplanin, Quino / dafoptin, tegacycline, ampicillin, and the positive rate of Streptococcus group B was 3.52%. The sensitivity rate of penicillin was 100.00% (180 cases), that of nitrofurantoin was 92.22% (166 cases) and that of ciprofloxacin was 82.22% (148 cases). The sensitivity rates to levofloxacin, ciprofloxacin and erythromycin were 81.11% (146 / 180), 55.00% (99 / 180) and 22.22% (40 / 180), respectively. The sensitive rates to clindamycin and tetracycline were 10.00% (18 / 180) and 7.78% (14 / 180) respectively. The results of routine examination of vaginal secretions of women carrying group B streptococcus showed that pH value of vaginal secretion was mainly pH 4.40 (77.78%) (140 cases). The degree of cleanliness was mainly grade 鈪，

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