【摘要】：目的通過對醫(yī)院近三年臨床標(biāo)本檢出耐碳青霉烯類腸桿菌科細(xì)菌(CRE)患者進行實時監(jiān)控分析,對臨床經(jīng)驗性治療及感染控制給予幫助。方法 2013年1月1日-2015年12月31日通過院感實時監(jiān)控系統(tǒng)進行前瞻性全面綜合性監(jiān)測,判定醫(yī)院感染、院外感染或定植,研究標(biāo)本及菌種來源、發(fā)現(xiàn)率變化、感染部位分布特征等。結(jié)果 2013-2015年共檢出CRE分離菌株111株,其中35株為醫(yī)院感染菌株、59株為院外感染菌株、17株為定植菌,呼吸道標(biāo)本占50.45%、血液標(biāo)本占6.31%、其他無菌體液標(biāo)本占13.51%;主要菌種來源:肺炎克雷伯菌占59.46%,大腸埃希菌占25.23%;2013-2015年院內(nèi)CRE發(fā)現(xiàn)率波動在0.108‰~0.224‰,院內(nèi)、院外及定植CRE發(fā)現(xiàn)率波動在0.346‰~0.734‰;院內(nèi)及院外CRE感染部位分布主要為下呼吸道感染,占46.81%,發(fā)生7例呼吸機相關(guān)性肺炎醫(yī)院感染,腹(盆)腔組織及腹水感染占12.77%,其中9例為院外感染。結(jié)論 2013-2015年CRE發(fā)現(xiàn)率呈上升趨勢,感染以下呼吸道為主,防止CRE的產(chǎn)生需對患者高危因素進行評估,進一步降低感染風(fēng)險,同時合理使用抗菌藥物。
[Abstract]:Objective to analyze the real-time monitoring and analysis of (CRE) patients with carbapenem resistant Enterobacteriaceae in clinical specimens in recent three years, and to provide help for clinical experience therapy and infection control. Methods from January 1, 2013 to December 31, 2015, a comprehensive and prospective monitoring system was used to determine nosocomial infection, nosocomial infection or colonization, study specimen and source of bacteria, and change of detection rate. Distribution of infection sites. Results A total of 111 strains of CRE were isolated in 2013-2015, of which 35 were nosocomial, 59 were nosocomial, 17 were colonized, 50.45in respiratory tract and 6.31 in blood. Other aseptic body fluid samples accounted for 13.51%. The main sources of bacteria were Klebsiella pneumoniae 59.46%, Escherichia coli 25.23%, and the detection rate of CRE ranged from 0.108 鈥，

本文編號：2335645