不同腹膜透析治療模式對透析患者鈣磷的代謝及PTH的影響
發(fā)布時間：2018-10-14 21:06
【摘要】：目的：探討日間非臥床腹膜透析(DAPD)對部分患者與經(jīng)典持續(xù)非臥床腹膜透析(CAPD)對患者鈣磷代謝及甲狀旁腺激素(PTH)的影響。方法：從新疆自治區(qū)人民醫(yī)院腎病科160名行腹膜透析患者中選取符合納入及排除標(biāo)準(zhǔn)的83例,年齡在20-80歲,平均年齡為(45.26±16.14)歲,根據(jù)不同透析方式分為兩組：CAPD組：共54例,男33例,女21例；DAPD組：共29例,男16例,女13例。CAPD組每日的透析劑量為6L-8L,日間進(jìn)行3次交換,每次留腹時間為5h,夜間交換1次,夜間留腹時間為9h(夜間留腹的透析液濃度為1.5%)；DAPD組透析劑量同CAPD組,但透析只在白天進(jìn)行,白天交換4次,每次交換時間為4h,夜間排空腹腔；觀察指標(biāo)：病人的一般資料、原發(fā)病、血紅蛋白(Hb)、血鈣(Ca)、血磷(P)、甲狀旁腺激素(PTH)、血漿白蛋白(ALB)、血肌酐(Scr)、甘油三酯(TG)、尿素氮(BUN)、超濾量以及殘余腎功能。實(shí)驗(yàn)數(shù)據(jù)以x±S表示,兩組間比較采用t檢驗(yàn),P0.05表示差異有統(tǒng)計(jì)學(xué)意義。結(jié)果：兩組在一般資料比較中差異無統(tǒng)計(jì)學(xué)意義(P0.05)；兩組治療一年后,DAPD組Hb、ALB、Scr、Ca、P、PTH、4h凈超濾量改善優(yōu)于CAPD組,并有統(tǒng)計(jì)學(xué)意義(P0.05)；兩組透前殘余腎功能無差異,但治療一年后DAPD組殘余腎功能優(yōu)于CAPD組,并有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論：行DAPD治療在改善鈣磷代謝及PTH等狀況優(yōu)于CAPD治療,并能更好的保護(hù)殘余腎功能。
[Abstract]:Objective: to investigate the effects of (DAPD) on calcium and phosphorus metabolism and parathyroid hormone (PTH) in some patients and in patients with classic continuous ambulatory peritoneal dialysis (CAPD). Methods: 83 peritoneal dialysis patients, aged 20-80 years, with an average age of (45.26 鹵16.14) years, were selected from 160 patients undergoing peritoneal dialysis in Renal Department of Xinjiang Autonomous region people's Hospital. According to different dialysis methods, they were divided into two groups: CAPD group: 54 cases. There were 33 males and 21 females in DAPD group: 29 patients, 16 males and 13 females. The dialytic dose of CAPD group was 6L-8L daily. Nocturnal peritoneal retention time was 9h (the concentration of nocturnal peritoneal dialysate was 1.5%); DAPD group dialysis dose was the same as that of CAPD group, but dialysis was only carried out during the day, the exchange time was 4 hours during the day, each time was 4 hours, the abdominal cavity was emptied at night. Primary, hemoglobin, (Hb), serum calcium, (Ca), serum phosphorus, (P), parathyroid hormone, (PTH), plasma albumin, serum creatinine, (Scr), triglyceride, (TG), urea nitrogen, (BUN), ultrafiltration and residual renal function. The experimental data were expressed as x 鹵S, and the difference between the two groups was statistically significant. Results: there was no significant difference in general data between the two groups (P0.05); after one year of treatment, the improvement of Hb,ALB,Scr,Ca,P,PTH,4h net ultrafiltration in DAPD group was better than that in CAPD group (P0.05); there was no difference in residual renal function before dialysis between the two groups. But one year after treatment, the residual renal function in DAPD group was better than that in CAPD group, and there was statistical significance (P0.05). Conclusion: DAPD is superior to CAPD in improving calcium and phosphorus metabolism and PTH, and can better protect residual renal function.
【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R459.5
，
本文編號：2271646
[Abstract]:Objective: to investigate the effects of (DAPD) on calcium and phosphorus metabolism and parathyroid hormone (PTH) in some patients and in patients with classic continuous ambulatory peritoneal dialysis (CAPD). Methods: 83 peritoneal dialysis patients, aged 20-80 years, with an average age of (45.26 鹵16.14) years, were selected from 160 patients undergoing peritoneal dialysis in Renal Department of Xinjiang Autonomous region people's Hospital. According to different dialysis methods, they were divided into two groups: CAPD group: 54 cases. There were 33 males and 21 females in DAPD group: 29 patients, 16 males and 13 females. The dialytic dose of CAPD group was 6L-8L daily. Nocturnal peritoneal retention time was 9h (the concentration of nocturnal peritoneal dialysate was 1.5%); DAPD group dialysis dose was the same as that of CAPD group, but dialysis was only carried out during the day, the exchange time was 4 hours during the day, each time was 4 hours, the abdominal cavity was emptied at night. Primary, hemoglobin, (Hb), serum calcium, (Ca), serum phosphorus, (P), parathyroid hormone, (PTH), plasma albumin, serum creatinine, (Scr), triglyceride, (TG), urea nitrogen, (BUN), ultrafiltration and residual renal function. The experimental data were expressed as x 鹵S, and the difference between the two groups was statistically significant. Results: there was no significant difference in general data between the two groups (P0.05); after one year of treatment, the improvement of Hb,ALB,Scr,Ca,P,PTH,4h net ultrafiltration in DAPD group was better than that in CAPD group (P0.05); there was no difference in residual renal function before dialysis between the two groups. But one year after treatment, the residual renal function in DAPD group was better than that in CAPD group, and there was statistical significance (P0.05). Conclusion: DAPD is superior to CAPD in improving calcium and phosphorus metabolism and PTH, and can better protect residual renal function.
【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R459.5
，
本文編號：2271646
本文鏈接：http://sikaile.net/huliyixuelunwen/2271646.html
最近更新
教材專著
