我院2011-2014年化膿性腦膜炎患者腦脊液病原菌分布及耐藥性分析
[Abstract]:Objective: to analyze the distribution and drug resistance of pathogenic bacteria in suppurative meningitis in our hospital. Methods: the pathogens of cerebrospinal fluid (CSF) from 4 255 patients with suppurative meningitis from January 1, 2011 to December 31, 2014 in our hospital were cultured, identified and tested. Results: a total of 834 strains of pathogenic bacteria were isolated and the positive rate was 19.6, including 576 Gram-positive bacteria (69.1%), 255 Gram-negative bacteria (30.6%) and 3 fungi (0.445%). The top 3 Gram-positive bacteria were coagulase negative Staphylococcus (436), Staphylococcus aureus (56) and Enterococcus (29), and Gram-negative bacteria were Klebsiella pneumoniae (46) and Acinetobacter baumannii (38). E. coli (31 strains). The top 3 pathogens were neurosurgery (506), intensive care unit (169) and respiratory intensive care (64). The results of drug sensitivity test showed that Staphylococcus and Enterococcus had no resistance to vancomycin, teicoplanin and minocycline, while non-fermentative gram-negative bacilli had lower resistance to minocycline. Conclusion: the detection rate of bacterial infection in cerebrospinal fluid of patients with suppurative meningitis in our hospital is mainly Gram-positive bacteria.
【作者單位】: 新疆醫(yī)科大學(xué)第一附屬醫(yī)院藥學(xué)部;新疆醫(yī)科大學(xué)第二附屬醫(yī)院藥劑科;
【分類號】:R515.2;R446.5
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