本文選題：頸動脈 + 動脈病變�。� 參考：《放射學實踐》2016年04期

【摘要】：目的:探討頸動脈狹窄程度與頸內(nèi)動脈血流動力學參數(shù)及相關(guān)腦區(qū)ADC值變化的關(guān)系。方法:27例患者經(jīng)磁共振血管成像(MRA)證實有中度以上頸動脈狹窄。所有患者行顱腦常規(guī)MRI、MRA和DWI檢查,并采用血流定量測量(QFlow)和彩色多普勒超聲(CDFI)對頸內(nèi)動脈的血流動力學參數(shù)進行分析。對QFlow技術(shù)與CDFI測量的血流參數(shù)(血流量、平均流速、峰值流速及管腔面積)及其與頸動脈狹窄程度及相關(guān)腦區(qū)的表觀擴散系數(shù)值(ADC)之間的相關(guān)性行非參數(shù)檢驗。結(jié)果:1QFlow技術(shù)與CDFI測量的血流量和平均流速呈中度正相關(guān)(r=0.695,P0.01;r=0.795,P0.01),峰值流速和管腔面積呈低度正相關(guān)(r=0.453,P0.01;r=0.573,P0.01)。2頸動脈狹窄程度與QFlow技術(shù)測量的頸內(nèi)動脈流量呈低度負相關(guān)(r=-0.467,P0.01),與側(cè)腦室旁前部和額葉白質(zhì)的ADC值呈低度正相關(guān)(r=0.373,P0.01;r=0.372,P0.01)。3側(cè)腦室旁前部和額葉白質(zhì)的ADC值與QFlow技術(shù)測量的頸內(nèi)動脈流量分別呈中度和低度負相關(guān)(r=-0.624,P0.01;r=-0.533,P0.01)。結(jié)論:多模態(tài)MRI能顯示頸動脈狹窄所致的頸內(nèi)動脈血流量減低及供血腦區(qū)的低灌注損傷,QFlow技術(shù)能較準確評價頸內(nèi)動脈血流動力學變化。
[Abstract]:Objective: to investigate the relationship between carotid stenosis and internal carotid artery hemodynamic parameters and ADC values in related brain regions. Methods 27 patients with moderate carotid artery stenosis were confirmed by magnetic resonance angiography (MRA). All patients were examined with conventional MRI MRA and DWI, and the hemodynamic parameters of internal carotid artery were analyzed by quantitative blood flow measurement (QFlow) and color Doppler ultrasound (CDFI). The blood flow parameters (blood flow, mean velocity, peak velocity and lumen area) measured by QFlow and CDFI, and their correlation with carotid stenosis and apparent diffusion coefficient (ADC) of the related brain region were examined by non-parametric test. Results the blood flow and mean flow velocity measured by CDFI were positively correlated (r 0.695U P 0.01n 0.795g P 0.01), the peak flow velocity was positively correlated with the lumen area (r 0.453P 0.01U 0.573P 0.01) .2 the degree of carotid artery stenosis was negatively correlated with the internal carotid artery flow measured by QFlow technique (r = -0.467P 0.01), and was negatively correlated with the flow of the internal carotid artery measured by QFlow technique (r = 0.467P 0.01), while the peak flow velocity was positively correlated with the lumen area (r = 0.453P 0.01n 0.573P 0.01). The ADC values of the anterior and frontal white matter of the paraventricular and frontal lobes showed a low positive correlation (r = 0.373U, P 0.01, P = 0.372P 0.01). 3 the ADC values of the anterior and frontal white matter of the paraventricular and frontal lobes were negatively correlated with the internal carotid artery flow measured by QFlow (r -0.624, P 0.01, P 0.01, P 0.01). Conclusion: multimodal MRI can accurately evaluate the changes of internal carotid artery hemodynamics by using QFlow technique to show the decrease of internal carotid artery blood flow caused by carotid stenosis and the low perfusion injury in the supplying brain area.
【作者單位】： 大連市第五人民醫(yī)院放射科;大連市第五人民醫(yī)院介入科;
【基金】：大連市科學技術(shù)局資助項目(2013E15SF151)
【分類號】：R445.2;R543.4

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