本文選題：嚴(yán)重膿毒血癥 + 連續(xù)性腎臟替代治療　； 參考：《重慶醫(yī)學(xué)》2016年08期

【摘要】：目的觀察連續(xù)性腎臟替代治療(CRRT)嚴(yán)重膿毒血癥的療效。方法選擇嚴(yán)重膿毒血癥患者22例,以行CRRT的患者作為治療組(n=11),同期未行CRRT而行常規(guī)治療的患者作為對照組(n=11)。兩組均動態(tài)觀察患者治療前后乳酸、降鈣素原、氧合指數(shù)、尿量等的變化,比較兩組療效及病死率。結(jié)果兩組患者疾病嚴(yán)重程度(APACHEⅡ評分)及器官衰竭水平(SOFA評分)比較,差異無統(tǒng)計學(xué)意義(P0.05),治療組短期內(nèi)乳酸、降鈣素原的下降,氧合指數(shù)的改善及尿量恢復(fù)均明顯優(yōu)于對照組,急性期(7d)病死率為9.1%,明顯低于對照組(36.4%);但呼吸機使用時間、腎功能恢復(fù)情況及總體生存率等長期預(yù)后指標(biāo)兩組比較,差異無統(tǒng)計學(xué)意義(P0.05)。結(jié)論 CRRT可提高嚴(yán)重膿毒血癥患者急性期搶救成功率,為原發(fā)病的治療創(chuàng)造條件,但對長期預(yù)后影響不大。
[Abstract]:Objective to observe the effect of continuous renal replacement therapy (CRRT) on severe sepsis. Methods 22 patients with severe sepsis were treated with CRRT as the treatment group, and those who were not treated with CRRT but with routine treatment were used as the control group. The changes of lactic acid, procalcitonin, oxygenation index and urine volume were observed before and after treatment. Results there was no significant difference between the two groups in the severity of disease (Apache 鈪，

本文編號：2044174