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磁共振電特性成像人體腹腔癌癥仿真研究

發(fā)布時間:2018-06-10 17:57

  本文選題:磁共振 + 電特性; 參考:《浙江大學(xué)學(xué)報(工學(xué)版)》2016年10期


【摘要】:將磁共振電特性成像(MREPT)方法用于人體腹腔部位,考察該成像方式用于人體腹腔肝癌及胰腺癌診斷的可行性.采用鳥籠線圈同時作為射頻發(fā)射和接收,基于射頻發(fā)射場測量值重構(gòu)人體腹腔內(nèi)組織的電導(dǎo)率和相對介電率.包含10種組織的人體腹腔模型上的仿真結(jié)果表明:在信噪比SNR=30的情況下,MREPT能夠檢測出位于組織內(nèi)部半徑為3cm的肝癌腫瘤和半徑為1cm的胰腺癌腫瘤;由于逆問題重構(gòu)公式中均質(zhì)電特性的假設(shè)及拉普拉斯卷積的共同作用,可能無法檢測出位于組織邊界處的小體積癌癥腫瘤.拉普拉斯卷積核的大小對重構(gòu)結(jié)果的影響很大,在無噪聲情況下,3×3×3的卷積核的重構(gòu)效果最好,但當(dāng)SNR=30~120時,5×5×5的卷積核是最佳選擇.
[Abstract]:The magnetic resonance electrical characteristic imaging (MRECT) method was used in the diagnosis of hepatocarcinoma and pancreatic cancer in human abdominal cavity. The bird cage coils are used as radiofrequency transmitting and receiving simultaneously. The conductivity and relative dielectric rate of human abdominal tissue are reconstructed based on the measurements of RF emission site. The simulation results on a human abdominal model containing 10 kinds of tissues show that MREPT can detect hepatocellular carcinoma with 3cm radius and pancreatic cancer with 1cm radius under SNR 30. Due to the assumption of homogeneous electrical properties in the inverse problem reconstruction formula and the interaction of Laplacian convolution, it may not be possible to detect small volume cancer tumors located at the tissue boundary. The size of Laplace convolution kernel has great influence on the reconstruction result. The reconstruction effect of 3 脳 3 脳 3 convolution kernel without noise is the best, but 5 脳 5 脳 5 convolution kernel is the best choice when SNRN is 30 ~ 120.
【作者單位】: 廈門理工學(xué)院電氣工程與自動化學(xué)院;休斯頓衛(wèi)理公會派醫(yī)院研究中心系統(tǒng)醫(yī)藥與生物工程系;廈門理工學(xué)院光電與通信工程學(xué)院;
【基金】:福建省自然科學(xué)基金資助項目(2013J05102;2016J01323) 福建省教育廳科研資助項目(JA15383)
【分類號】:R445.2;R735;TP391.9
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本文編號:2004101

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