2011-2014年ICU多藥耐藥菌流行病學(xué)分析研究
發(fā)布時(shí)間:2018-06-05 17:18
本文選題:重癥監(jiān)護(hù)病房 + 醫(yī)院感染 ; 參考:《中華醫(yī)院感染學(xué)雜志》2016年02期
【摘要】:目的了解ICU多藥耐藥菌(MDROs)分布特點(diǎn)及流行趨勢(shì),為指導(dǎo)MDROs預(yù)防控制措施提供依據(jù)。方法前瞻性監(jiān)測(cè)某三級(jí)醫(yī)院2011-2014年ICU住院患者1 231株病原菌構(gòu)成比、MDROs檢出率及標(biāo)本分布等流行特征;采用SPSS17.0軟件對(duì)數(shù)據(jù)進(jìn)行統(tǒng)計(jì)分析。結(jié)果 2011-2014年ICU革蘭陰性菌構(gòu)成比均78.0%,其中2013年高達(dá)91.79%,以鮑氏不動(dòng)桿菌、銅綠假單胞菌、肺炎克雷伯菌為主,革蘭陽(yáng)性菌以金黃色葡萄球菌為主;MDROs總檢出率4年差異有統(tǒng)計(jì)學(xué)意義(χ2=21.638,P0.05),2013年檢出率最高,為56.72%,2011年最低,為41.44%,標(biāo)本來源以痰液為主。結(jié)論 ICU醫(yī)院感染多見于下呼吸道,以革蘭陰性菌為主,通過實(shí)施目標(biāo)性監(jiān)測(cè),加強(qiáng)MDROs預(yù)防及控制措施落實(shí),MDROs感染控制有下降趨勢(shì),但仍是預(yù)防控制重點(diǎn)科室。
[Abstract]:Objective to investigate the distribution and epidemic trend of ICU multidrug resistant bacteria (MDROs), and to provide evidence for guiding the prevention and control of MDROs. Methods the prevalence characteristics of 1 231 strains of pathogenic bacteria in ICU inpatients in a tertiary hospital from 2011 to 2014 were prospectively monitored, and the data were statistically analyzed by SPSS17.0 software. Results the composition ratio of Gram-negative bacteria in ICU from 2011 to 2014 was 78.0, among which 91.79 were found in 2013. Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae were the main components. The total detection rate of MDROs in Gram-positive bacteria was significantly different from that of Staphylococcus aureus in 4 years (蠂 ~ (2 +) 21.638U P 0.05), the highest rate was 56.72 in 2013, and the lowest was 41.44 in 2011. Sputum was the main source of specimens. Conclusion ICU nosocomial infection is more common in lower respiratory tract, mainly Gram-negative bacteria. Through the implementation of targeted surveillance, MDROs prevention and control measures to implement the MDROs infection control has a downward trend, but it is still the key department of prevention and control.
【作者單位】: 濱州醫(yī)學(xué)院附屬醫(yī)院護(hù)理部;濱州醫(yī)學(xué)院附屬醫(yī)院醫(yī)院感染管理辦公室;濱州醫(yī)學(xué)院附屬醫(yī)院藥學(xué)部;濱州醫(yī)學(xué)院附屬醫(yī)院微生物室;
【基金】:山東省醫(yī)藥衛(wèi)生科技發(fā)展基金資助項(xiàng)目(2011HW056) 山東省濱州市科技發(fā)展計(jì)劃基金資助項(xiàng)目(2013ZC1802;2013ZC1714;2013ZC1711) 中華醫(yī)院感染控制研究基金資助項(xiàng)目(ZHYY2014-0027)
【分類號(hào)】:R446.5
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