本文選題：多重耐藥菌(MDROs) + 定植��； 參考：《中國(guó)公共衛(wèi)生》2016年11期

【摘要】：目的了解重癥監(jiān)護(hù)病房(ICU)患者多重耐藥菌(MDROs)定植情況及其危險(xiǎn)因素,為MDROs的預(yù)防和控制提供參考依據(jù)。方法整群抽取東南大學(xué)附屬中大醫(yī)院2014年1月—2015年12月ICU收治的1143例患者進(jìn)行病例收集,并采集其鼻前庭及咽拭子進(jìn)行細(xì)菌培養(yǎng)和藥敏試驗(yàn)。結(jié)果 ICU中1 143例患者發(fā)生MDROs定植者217例,MDROs定植發(fā)生率為18.99%;217例MDROs定植者中,發(fā)生多重耐藥金黃色葡萄球菌定植者27例(12.44%),多重耐藥肺炎克雷伯菌定植者122例(56.22%),多重耐藥鮑曼不動(dòng)桿菌定植者41例(18.89%),多重耐藥銅綠假單胞菌定植者27例(12.44%);多因素非條件logistic回歸分析結(jié)果顯示,入ICU前抗菌藥物使用種類2種(OR=2.011,95%CI=1.081~4.552)和入ICU前抗菌藥物使用時(shí)間≥3d(OR=4.201,95%CI=2.108~5.011)是ICU患者M(jìn) DROs定植發(fā)生的危險(xiǎn)因素。結(jié)論 ICU患者M(jìn) DROs定植發(fā)生率較高,以多重耐藥肺炎克雷伯菌定植為主;入ICU前抗菌藥物使用種類較多和入ICU前抗菌藥物使用時(shí)間較長(zhǎng)是ICU患者M(jìn)DROs定植發(fā)生的主要危險(xiǎn)因素。
[Abstract]:Objective to investigate the colonization and risk factors of multidrug resistant bacteria (MDR) in patients with ICU in intensive care unit (ICU), and to provide reference for the prevention and control of MDROs. Methods 1143 patients admitted to ICU from January 2014 to December 2015 were collected by cluster sampling and their nasal vestibule and throat swabs were collected for bacterial culture and drug sensitivity test. Results the incidence of MDROs colonization in 1 143 cases of ICU was 18. 99%, and the incidence of MDROs colonization was 18. 99% in 217 cases of MDROs colonization. There were 27 cases of multidrug resistant Staphylococcus aureus colonization, 122 cases of multidrug resistant Klebsiella pneumoniae colonization, 41 cases of Acinetobacter baumannii colonization, 27 cases of multidrug resistance Pseudomonas aeruginosa colonization 12.4444 and 27 cases of multidrug resistant Pseudomonas aeruginosa colonization. The results of non-conditional logistic regression analysis showed that, The risk factors of M DROs colonization in ICU patients were two kinds of antimicrobial agents used before ICU (2.0111195) and before ICU (鈮，

本文編號(hào)：1904667