本文選題：高通量測序 + 嚴重感染��； 參考：《中國病原生物學雜志》2016年09期

【摘要】：如何能在海量的高通量測序數(shù)據(jù)中去除噪音、發(fā)現(xiàn)致病微生物是一個重要的研究課題。臨床信息指導下的高通量測序能減少對于高通量測序海量數(shù)據(jù)的生物信息學分析工作量,高通量測序指導下的病原體致病性判斷又減少了臨床撒網式篩查病原體的工作量。高通量測序的臨床應用可能使得嚴重感染的臨床治療更為精準并有效降低死亡率。
[Abstract]:How to remove noise from massive high throughput sequencing data and find pathogenic microorganisms is an important research topic. The high-throughput sequencing under the guidance of clinical information can reduce the workload of bioinformatics analysis of mass data of high-throughput sequencing, and the pathogenicity judgment of pathogens guided by high-throughput sequencing can also reduce the workload of screening pathogens. High-throughput sequencing clinical applications may make the clinical treatment of severe infections more accurate and effective in reducing mortality.
【作者單位】： 首都醫(yī)科大學附屬北京友誼醫(yī)院北京熱帶醫(yī)學研究所熱帶病防治研究北京市重點實驗室;北京大學第一醫(yī)院;中國人民解放軍軍事醫(yī)學科學院微生物流行病研究所;
【分類號】：R440
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本文編號：1827020