發(fā)布時(shí)間：2018-03-30 23:09

  本文選題：青年人群　切入點(diǎn)：臂踝動(dòng)脈脈搏波傳導(dǎo)速度　出處：《中華高血壓雜志》2016年04期

【摘要】：目的探討青年人群臂踝動(dòng)脈脈搏波傳導(dǎo)速度(baPWV)、頸動(dòng)脈內(nèi)膜中層厚度(IMT)和血流介導(dǎo)的血管舒張功能(FMD)的相關(guān)性。方法對(duì)陜西漢中老君鄉(xiāng)10個(gè)自然村人群心血管病危險(xiǎn)因素進(jìn)行調(diào)查,選取其中完成IMT、FMD、baPWV 3項(xiàng)檢查,符合入排標(biāo)準(zhǔn)的30~45歲青年人群473名進(jìn)行體格及生化指標(biāo)檢查。BP-203RPEⅢ動(dòng)脈硬化檢測(cè)儀測(cè)量baPWV,超聲檢測(cè)IMT和FMD。應(yīng)用Pearson相關(guān)和多元線性回歸分析baPWV與IMT、FMD的相關(guān)性。結(jié)果與男性相比,女性FMD值較高[(10.28±4.25)%比(9.38±4.40)%,P0.05],baPWV值較低[(12.26±2.05)m/s比(13.59±1.96)m/s,P0.01],兩者IMT水平差異無(wú)統(tǒng)計(jì)學(xué)意義。Pearson相關(guān)分析結(jié)果顯示,IMT與FMD、baPWV的相關(guān)性無(wú)統(tǒng)計(jì)學(xué)意義,FMD和baPWV則呈負(fù)相關(guān)(r=-0.35,P0.01)。多元線性回歸分析校正性別、年齡、收縮壓、舒張壓、體質(zhì)量指數(shù)、腰臀比、三酰甘油、總膽固醇、低密度脂蛋白膽固醇、高密度脂蛋白膽固醇、空腹血糖、血肌酐、血尿酸等心血管病相關(guān)因素后,發(fā)現(xiàn)FMD是baPWV的影響因素(B=-8.689,P0.01)。結(jié)論在本組青年人群中,baPWV和FMD呈負(fù)相關(guān),而IMT與baPWV及FMD均無(wú)相關(guān)性。
[Abstract]:Objective to investigate the correlation between brachial malleolus pulse wave velocity (PWV), carotid intima-media thickness (IMT) and blood flow mediated vasodilation (FMD) in young people.Methods the risk factors of cardiovascular disease in 10 natural villages in Laojun Township, Hanzhong, Shaanxi Province were investigated, and three items of IMT FMDA PWV were selected.A total of 473 young people aged 30 to 45 years old who met the admission criteria were examined with physical and biochemical indexes. The baPWV was measured by BP-203 RPE 鈪，

本文編號(hào)：1688057