本文關(guān)鍵詞： 金黃色葡萄球菌 醫(yī)院感染 耐藥性　出處：《中國消毒學(xué)雜志》2016年09期 　論文類型：期刊論文

【摘要】：目的了解醫(yī)院住院患者金黃色葡萄球菌感染分布特征及耐藥性,為臨床選擇抗菌藥物防控其感染提供依據(jù)。方法采用病原菌分離鑒定和藥敏試驗(yàn)方法,對某醫(yī)院臨床送檢病原學(xué)標(biāo)本進(jìn)行檢測并對結(jié)果進(jìn)行統(tǒng)計(jì)分析。結(jié)果從該醫(yī)院住院患者送檢病原學(xué)標(biāo)本中共檢出金黃色葡萄球菌201株,其中有46.7%分離自痰液、有20.0%分離自膿液,分離自分泌物標(biāo)本占17.4%。臨床分離的金黃色葡萄球菌對萬古霉素、替考拉寧和利奈唑胺等抗菌藥物全部敏感;對其他臨床常用抗菌藥物呈現(xiàn)出不同耐藥性;耐甲氧西林金黃色葡萄球菌(MRSA)對慶大霉素、氨芐西林和頭孢唑林等抗菌藥物的耐藥率明顯高于甲氧西林敏感菌株。結(jié)論該醫(yī)院臨床分離的金黃色葡萄球菌主要分離自痰液、膿液和分泌物,耐藥性嚴(yán)重,提示應(yīng)加強(qiáng)藥敏試驗(yàn),并以此指導(dǎo)臨床選擇抗菌藥物。
[Abstract]:Objective to investigate the distribution characteristics and drug resistance of Staphylococcus aureus infection in hospitalized patients, and to provide the basis for clinical selection of antimicrobial agents to prevent and control their infection. Results A total of 201 strains of Staphylococcus aureus were detected from the pathogenic specimens of hospitalized patients in a hospital, of which 46.7% strains were isolated from sputum and 20.0% strains from pus. The clinical isolates of Staphylococcus aureus were all sensitive to vancomycin, teicoplanin and linazolamide, and showed different drug resistance to other commonly used antibiotics. The resistant rate of MRSAs to gentamicin, ampicillin and cefazolin was significantly higher than that of methicillin-sensitive strains. Conclusion Staphylococcus aureus isolated clinically in this hospital was mainly isolated from sputum. The drug resistance of pus and secretions is serious, which suggests that antimicrobial susceptibility test should be strengthened to guide clinical selection of antimicrobial agents.
【作者單位】： 湖北省疾病預(yù)防控制中心;重慶醫(yī)科大學(xué)公共衛(wèi)生與管理學(xué)院;
【分類號】：R446.5

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