發(fā)布時(shí)間：2018-02-16 01:08

  本文關(guān)鍵詞： 銅綠假單胞菌 黏液型 藥物敏感性 多藥耐藥菌　出處：《中華醫(yī)院感染學(xué)雜志》2016年17期 　論文類(lèi)型：期刊論文

【摘要】：目的分析醫(yī)院2010-2014年分離出的黏液型銅綠假單胞菌的藥物敏感性及多藥耐藥菌的檢出情況,為臨床及時(shí)、合理用藥提供參考依據(jù)。方法對(duì)分離出的黏液型銅綠假單胞菌進(jìn)行藥物敏感性檢測(cè),同時(shí)對(duì)多藥耐藥菌的檢出率進(jìn)行統(tǒng)計(jì)。結(jié)果黏液型銅綠假單胞菌對(duì)常見(jiàn)抗菌藥物的敏感率均75.0%,對(duì)大部分抗菌藥物的敏感率逐年下降;與非黏液型銅綠假單胞菌相比,黏液型銅綠假單胞菌的敏感率較高;門(mén)診患者對(duì)頭孢他啶和環(huán)丙沙星的敏感率高于住院患者(P0.05);呼吸內(nèi)科患者對(duì)頭孢他啶的敏感率低于其他非呼吸科室(P0.05);多藥耐藥黏液型銅綠假單胞菌檢出率9.0%,泛耐藥黏液型銅綠檢出率0.9%,均低于非黏液型銅綠假單胞菌。結(jié)論黏液型銅綠假單胞菌藥物敏感率較高,但呈逐年下降趨勢(shì);其多藥耐藥菌檢出率逐年遞增;治療黏液型銅綠假單胞菌感染時(shí)應(yīng)注意其生物膜影響,可聯(lián)合用藥,避免抗菌藥物濫用,以減緩多藥耐藥菌的產(chǎn)生。
[Abstract]:Objective to analyze the drug sensitivity and multidrug resistance of Pseudomonas aeruginosa isolated from 2010 to 2014. Methods the drug sensitivity of Pseudomonas aeruginosa isolated from myxomonas aeruginosa was detected. Results the sensitivity rate of Pseudomonas aeruginosa to common antimicrobial agents was 75.0, and the sensitivity rate to most antimicrobial agents decreased year by year, compared with that of non-mucinous Pseudomonas aeruginosa, and compared with that of non-mucinous Pseudomonas aeruginosa, the sensitivity of Pseudomonas aeruginosa to common antimicrobial agents decreased year by year. The sensitivity of Pseudomonas aeruginosa was higher than that of Pseudomonas aeruginosa. The sensitivity of outpatients to ceftazidime and ciprofloxacin was higher than that of inpatients (P 0.05), the sensitivity of respiratory patients to ceftazidime was lower than that of other non-respiratory departments (P0.05), and the detection rate of multidrug resistant myxomonas aeruginosa was 9.0%. The detection rate of myxotypic Pseudomonas aeruginosa was 0.9, which was lower than that of non-mucinous Pseudomonas aeruginosa. Conclusion the drug sensitivity rate of mucus type Pseudomonas aeruginosa is higher. The detection rate of multidrug resistant bacteria increased year by year, and the biofilm effect should be paid attention to in the treatment of myxomonas aeruginosa infection, which could be used in combination to avoid the abuse of antimicrobial agents in order to slow down the production of multidrug resistant bacteria.
【作者單位】： 臨沂市人民醫(yī)院;浙江大學(xué)醫(yī)學(xué)院附屬第一醫(yī)院傳染病診治國(guó)家重點(diǎn)實(shí)驗(yàn)室;日照市莒縣中醫(yī)院;
【基金】：國(guó)家自然科學(xué)基金資助項(xiàng)目(81400586)
【分類(lèi)號(hào)】：R446.5

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