原發(fā)性高血壓動態(tài)動脈硬化指數與頸動脈彈性功能的相關性
發(fā)布時間:2018-02-09 15:51
本文關鍵詞: 原發(fā)性高血壓 動脈粥樣硬化 動態(tài)動脈硬化指數 血管回聲跟蹤技術 頸動脈 彈性 出處:《中國超聲醫(yī)學雜志》2016年11期 論文類型:期刊論文
【摘要】:目的探討原發(fā)性高血壓動態(tài)動脈硬化指數與頸動脈彈性功能改變的相關性。方法選擇原發(fā)性高血壓患者104例和對照組健康成人50例,二維超聲檢測頸動脈內-中膜厚度(IMT),應用血管回聲跟蹤技術(ET)檢測受檢者頸總動脈僵硬度、壓力應變系數、順應性、增大指數、單點脈搏傳播速度等彈性功能參數,將原發(fā)性高血壓患者按IMT≥1.0mm者為頸動脈硬化組,1.0mm者為無頸動脈硬化組。通過24h動態(tài)血壓監(jiān)測,計算動態(tài)動脈硬化指數(AASI)。分析AASI與頸動脈彈性功能參數的相關性。結果原發(fā)性高血壓患者和對照組動態(tài)動脈硬化指數分別為0.56±0.14和0.41±0.12(P0.01);高血壓頸動脈硬化組和無頸動脈硬化組動態(tài)動脈硬化指數分別為0.59±0.12和0.50±0.11(P0.05);AASI與頸動脈僵硬度、壓力應變系數、膨大指數、單點脈搏傳導速度呈正相關(r=0.336、0.269、0.274、0.356,均P0.05),與順應性呈負相關(r=-0.282,P0.01)。與對照組比較,高血壓組頸動脈僵硬度指數、壓力應變系數、膨大指數、單點脈搏傳導速度增大,順應性降低(P0.05)。結論動態(tài)動脈硬化指數可以反映頸動脈硬化及彈性功能改變。原發(fā)性高血壓動態(tài)動脈硬化指數與頸動脈粥樣硬化關系密切。
[Abstract]:Objective to investigate the relationship between dynamic arteriosclerosis index and carotid elastic function in patients with essential hypertension. Methods 104 patients with essential hypertension and 50 healthy adults were selected. Carotid intima-media thickness (IMT) was measured by two-dimensional ultrasound, and elastic parameters such as common carotid artery stiffness, pressure strain coefficient, compliance, increase index, pulse velocity at single point were measured by vascular echo tracking technique (ETT). The patients with essential hypertension were divided into carotid atherosclerosis group (IMT 鈮,
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