兒童中樞性性早熟的臨床與影像學(xué)表現(xiàn)分析
發(fā)布時(shí)間:2018-01-07 06:27
本文關(guān)鍵詞:兒童中樞性性早熟的臨床與影像學(xué)表現(xiàn)分析 出處:《臨床放射學(xué)雜志》2016年06期 論文類型:期刊論文
更多相關(guān)文章: 性早熟 磁共振成像 中樞神經(jīng)系統(tǒng)
【摘要】:目的分析引起兒童中樞性性早熟的常見(jiàn)病因及影像學(xué)表現(xiàn),從而提高其診斷水平。方法回顧性分析7年內(nèi)經(jīng)臨床、實(shí)驗(yàn)室檢查、影像及病理檢查確診的33例中樞性性早熟患兒的臨床及影像學(xué)資料。結(jié)果 33例患兒均行影像學(xué)檢查,17例(女9例,男8例)發(fā)現(xiàn)器質(zhì)性病變,包括下丘腦錯(cuò)構(gòu)瘤6例,空蝶鞍3例,生殖細(xì)胞瘤3例,惡性畸胎瘤1例,胼胝體脂肪瘤1例,膠質(zhì)瘤2例(其中1例為NF-Ⅰ型),鞍上池蛛網(wǎng)膜囊腫1例;2例合并腦積水。16例(女15例,男1例)未發(fā)現(xiàn)器質(zhì)性病變,診斷為特發(fā)性性早熟。結(jié)論兒童中樞性性早熟包括特發(fā)性和器質(zhì)性性早熟,女孩大多數(shù)為特發(fā)性性早熟,而男孩多為器質(zhì)性性早熟。因此,對(duì)于4歲的女孩及所有男孩,性早熟發(fā)展迅速,有神經(jīng)系統(tǒng)的癥狀和體征,實(shí)驗(yàn)室檢查提示病理性性早熟者均應(yīng)行頭顱影像學(xué)檢查,腦部MRI是排除器質(zhì)性性早熟的基本檢查方法。
[Abstract]:Objective to analyze the common causes and imaging manifestations of central precocious puberty in children so as to improve the diagnostic level. Methods Clinical and laboratory examinations within 7 years were retrospectively analyzed. The clinical and imaging data of 33 children with central precocious puberty were confirmed by imaging and pathological examination. Results 17 cases (9 female and 8 male) of organic diseases were found by imaging examination in all 33 cases. There were 6 cases of hypothalamic hamartoma, 3 cases of empty Sella, 3 cases of germ cell tumor, 1 case of malignant teratoma, 1 case of corpus callosum lipoma and 2 cases of glioma (1 case was NF- 鈪,
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